Laboratory of Genomic Editing

Creation of cell lines with a modified genome by methods of directed genomic editing Development of modified guide RNAs to regulate the activity of genomic editing systems Development of approaches to the synthesis of artificial mRNAs to create therapeutic agents and mRNA vaccines Study of the properties and functions of small regulatory RNAs in order to create new means of regulating gene expression Basic project Basic project. The National Science Project. No. 122022100238-7 (Youth Laboratories) "Creation of methods and approaches for genomic editing technology" (2022-2024) Grants from the Russian Science Foundation No. 22-75-10153 "Structural features of mRNA determining the effectiveness of immune response formation on the mRNA vaccine model against influenza virus" No. 21-64-00017 "Modification of nucleic acids and DNA repair as a source of new genome management tools" No. 18-75-10069 "Development of a strategy for the creation of highly transmissive influenza virus cell lines for the production of vaccine preparations" (2018-2021) RFBR grants No. 18-29-07073 "m" "Development of a universal strategy for selective inhibition of splicing by editing small nucleolar RNA genes" (2018-2021) No. 19-34-90168 Graduate students "Determining the role of small nucleolar RNAs in the regulation of infection human cells with influenza A virus" (2019-2021)