Open Access
MolBank, volume 2021, issue 3, pages M1253
4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine
Rakitin Oleg A.
1, 2
Publication type: Journal Article
Publication date: 2021-07-22
DOI:
10.3390/M1253
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A novel 4-chloro-6-(chloromethyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine was prepared by a rational and short two-step synthesis from commercially available ethyl 5-amino-1-methyl-1H-pyrazole-4-carboxylate via 6-(chloromethyl)-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one. The structure of the synthesized compounds was established by elemental analysis, high-resolution mass-spectrometry, 1H, 13C-NMR and IR spectroscopy and mass-spectrometry. 4-Chloro-6-(chloromethyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine is a convenient intermediate for various disubstituted 1-methyl-1H-pyrazolo[3,4-d]pyrimidines, which may be of interest as substances with useful pharmacological properties.
Citations by journals
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1
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MolBank
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MolBank
1 publication, 50%
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Arabian Journal of Chemistry
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Arabian Journal of Chemistry
1 publication, 50%
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1
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Citations by publishers
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1
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
1 publication, 50%
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King Saud University
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King Saud University
1 publication, 50%
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1
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- Statistics recalculated weekly.
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Ogurtsov V., Rakitin O. A. 4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine // MolBank. 2021. Vol. 2021. No. 3. p. M1253.
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Ogurtsov V., Rakitin O. A. 4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine // MolBank. 2021. Vol. 2021. No. 3. p. M1253.
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TY - JOUR
DO - 10.3390/M1253
UR - https://doi.org/10.3390%2FM1253
TI - 4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine
T2 - MolBank
AU - Ogurtsov, Vladimir
AU - Rakitin, Oleg A.
PY - 2021
DA - 2021/07/22 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - M1253
IS - 3
VL - 2021
SN - 1422-8599
ER -
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BibTex
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@article{2021_Ogurtsov,
author = {Vladimir Ogurtsov and Oleg A. Rakitin},
title = {4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine},
journal = {MolBank},
year = {2021},
volume = {2021},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jul},
url = {https://doi.org/10.3390%2FM1253},
number = {3},
pages = {M1253},
doi = {10.3390/M1253}
}
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MLA
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Ogurtsov, Vladimir, et al. “4-chloro-6-(Chloromethyl)-1-methyl-1h-pyrazolo[3,4-d]pyrimidine.” MolBank, vol. 2021, no. 3, Jul. 2021, p. M1253. https://doi.org/10.3390%2FM1253.