Open Access
Open access
MolBank, volume 2021, issue 4, pages M1294

6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine

Publication typeJournal Article
Publication date2021-11-01
Journal: MolBank
Quartile SCImago
Q4
Quartile WOS
Impact factor0.4
ISSN14228599
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract

Functionally 4,6-disubstituted 1H-pyrazolo[3,4-d]pyrimidines are important compounds with various pharmacological activities. 1-Substituted 4-chloro-6-(chloromethyl)-1H-pyrazolo[3,4-d]pyrimidines are practically unexplored derivatives in this series. In this paper, it was shown that the nucleophilic substitution of 4-Chloro-6-(chloromethyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine with methylamine produced selectively 4-substituted product, 6-(chloromethyl)-N,1-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine. The structure of the synthesized compound was established by elemental analysis, high resolution mass-spectrometry, 1H, 13C-NMR, and IR spectroscopy, mass-spectrometry, and X-ray analysis.

Citations by journals

1
Zeitschrift fur Kristallographie - New Crystal Structures
Zeitschrift fur Kristallographie - New Crystal Structures, 1, 100%
Zeitschrift fur Kristallographie - New Crystal Structures
1 publication, 100%
1

Citations by publishers

1
Walter de Gruyter
Walter de Gruyter, 1, 100%
Walter de Gruyter
1 publication, 100%
1
  • We do not take into account publications that without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Ogurtsov V. A., Rakitin O. A. 6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine // MolBank. 2021. Vol. 2021. No. 4. p. M1294.
GOST all authors (up to 50) Copy
Ogurtsov V. A., Rakitin O. A. 6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine // MolBank. 2021. Vol. 2021. No. 4. p. M1294.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/M1294
UR - https://doi.org/10.3390%2FM1294
TI - 6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine
T2 - MolBank
AU - Ogurtsov, Vladimir A.
AU - Rakitin, Oleg A.
PY - 2021
DA - 2021/11/01 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - M1294
IS - 4
VL - 2021
SN - 1422-8599
ER -
BibTex |
Cite this
BibTex Copy
@article{2021_Ogurtsov
author = {Vladimir A. Ogurtsov and Oleg A. Rakitin},
title = {6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine},
journal = {MolBank},
year = {2021},
volume = {2021},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {nov},
url = {https://doi.org/10.3390%2FM1294},
number = {4},
pages = {M1294},
doi = {10.3390/M1294}
}
MLA
Cite this
MLA Copy
Ogurtsov, Vladimir A., and Oleg A. Rakitin. “6-(Chloromethyl)-n,1-dimethyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine.” MolBank, vol. 2021, no. 4, Nov. 2021, p. M1294. https://doi.org/10.3390%2FM1294.
Found error?