Open Access
Bioengineering, издание 9, том 5, страницы 210
Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid
Guseva Galina B
1
,
Antina Elena V.
1
,
Smirnova Anastassia S
1, 2
,
Gilfanov Ilmir R.
3, 4
,
Pestova Svetlana V
6
,
Rubtsova Svetlana A.
6
,
Ostolopovskaya Olga V
3, 7
,
Efimov Sergey
3
,
Rakhmatullin Ilfat Z.
3
,
Timerova Ayzira F
3
,
Khodov Ilya A.
1
,
Islamov Daut R.
9
,
Nikitina Liliya E.
3, 7
,
Boichuk Sergei
3, 7
8
Тип публикации: Journal Article
Дата публикации: 2022-05-12
Multidisciplinary Digital Publishing Institute (MDPI)
Журнал:
Bioengineering
Квартиль SCImago: Q2
Квартиль WOS: Q2
Impact factor: 4.6
ISSN: 23065354
PubMed ID:
35621488
Bioengineering
Краткое описание
This paper presents the design and a comparative analysis of the structural and solvation factors on the spectral and biological properties of the BODIPY biomarker with a thioterpene fragment. Covalent binding of the thioterpene moiety to the butanoic acid residue of meso-substituted BODIPY was carried out to find out the membranotropic effect of conjugate to erythrocytes, and to assess the possibilities of its practical application in bioimaging. The molecular structure of the conjugate was confirmed via X-ray, UV/vis-, NMR-, and MS-spectra. It was found that dye demonstrates high photostability and high fluorescence quantum yield (to ~100%) at 514–519 nm. In addition, the marker was shown to effectively penetrate the erythrocytes membrane in the absence of erythrotoxicity. The conjugation of BODIPY with thioterpenoid is an excellent way to increase affinity dyes to biostructures, including blood components.
Цитирования по журналам
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1
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Journal of Photochemistry and Photobiology A: Chemistry
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Journal of Photochemistry and Photobiology A: Chemistry
1 публикация, 100%
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1
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Цитирования по издателям
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1
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Elsevier
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Elsevier
1 публикация, 100%
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1
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Guseva G. B. et al. Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid // Bioengineering. 2022. Vol. 9. No. 5. p. 210.
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Guseva G. B., Antina E. V., Berezin M. B., Smirnova A. S., Pavelyev R. S., Gilfanov I. R., Shevchenko O. G., Pestova S. V., Izmest’ev E. S., Rubtsova S. A., Ostolopovskaya O. V., Efimov S., Klochkov V. V., Rakhmatullin I. Z., Timerova A. F., Khodov I. A., Lodochnikova O. A., Islamov D. R., Dorovatovskii P. V., Nikitina L. E., Boichuk S. Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid // Bioengineering. 2022. Vol. 9. No. 5. p. 210.
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TY - JOUR
DO - 10.3390/bioengineering9050210
UR - https://doi.org/10.3390/bioengineering9050210
TI - Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid
T2 - Bioengineering
AU - Berezin, Mikhail B
AU - Smirnova, Anastassia S
AU - Shevchenko, Oksana G.
AU - Pestova, Svetlana V
AU - Rubtsova, Svetlana A.
AU - Ostolopovskaya, Olga V
AU - Rakhmatullin, Ilfat Z.
AU - Timerova, Ayzira F
AU - Dorovatovskii, Pavel V.
AU - Antina, Elena V.
AU - Islamov, Daut R.
AU - Guseva, Galina B
AU - Pavelyev, Roman S.
AU - Gilfanov, Ilmir R.
AU - Izmest’ev, Evgeniy S.
AU - Efimov, Sergey
AU - Klochkov, Vladimir V.
AU - Khodov, Ilya A.
AU - Lodochnikova, Olga A.
AU - Nikitina, Liliya E.
AU - Boichuk, Sergei
PY - 2022
DA - 2022/05/12 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 210
IS - 5
VL - 9
PMID - 35621488
SN - 2306-5354
ER -
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@article{2022_Guseva
author = {Mikhail B Berezin and Anastassia S Smirnova and Oksana G. Shevchenko and Svetlana V Pestova and Svetlana A. Rubtsova and Olga V Ostolopovskaya and Ilfat Z. Rakhmatullin and Ayzira F Timerova and Pavel V. Dorovatovskii and Elena V. Antina and Daut R. Islamov and Galina B Guseva and Roman S. Pavelyev and Ilmir R. Gilfanov and Evgeniy S. Izmest’ev and Sergey Efimov and Vladimir V. Klochkov and Ilya A. Khodov and Olga A. Lodochnikova and Liliya E. Nikitina and Sergei Boichuk},
title = {Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid},
journal = {Bioengineering},
year = {2022},
volume = {9},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {may},
url = {https://doi.org/10.3390/bioengineering9050210},
number = {5},
pages = {210},
doi = {10.3390/bioengineering9050210}
}
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Guseva, Galina B., et al. “Design, Spectral Characteristics, Photostability, and Possibilities for Practical Application of BODIPY FL-Labeled Thioterpenoid.” Bioengineering, vol. 9, no. 5, May. 2022, p. 210. https://doi.org/10.3390/bioengineering9050210.