Open Access

Cells

, volume 9 , issue 7 , pages 1620

Molecular Basis of the Function of Transcriptional Enhancers

Airat N Ibragimov ^{1, 2}

Oleg V Bylino ¹

Y. V. Shidlovskii ^{1, 3}

Hide authors affiliations Show authors affiliations: 3 affiliations

Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., 119334 Moscow, Russia |

Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., 119334 Moscow, Russia |

I.M. Sechenov First Moscow State Medical University, 8, bldg. 2 Trubetskaya St., 119048 Moscow, Russia |

Publication type: Journal Article

Publication date: 2020-07-05

MDPI

Cells

scimago Q1

wos Q2

SJR: 1.670

CiteScore: 10.5

Impact factor: 5.2

ISSN: 20734409

DOI: 10.3390/cells9071620

Copy DOI

PubMed ID: 32635644

General Medicine

Abstract

Transcriptional enhancers are major genomic elements that control gene activity in eukaryotes. Recent studies provided deeper insight into the temporal and spatial organization of transcription in the nucleus, the role of non-coding RNAs in the process, and the epigenetic control of gene expression. Thus, multiple molecular details of enhancer functioning were revealed. Here, we describe the recent data and models of molecular organization of enhancer-driven transcription.

Found

3 citations

Shidlovskii Yulii

🥼 🤝

DSc in Biological/biomedical sciences, professor

85 publications, 1 017 citations

h-index: 17

Institute of Gene Biology of the Russian Academy of Sciences

Sechenov First Moscow State Medical University

2 citations

Kotova Elena

PhD in Biological/biomedical sciences

12 publications, 49 citations

h-index: 4

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency

Research interests

Chromatin

Genetic engineering

Mechanisms of epigenetic regulation of transcription

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GOST |

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GOST Copy

Ibragimov A. N. et al. Molecular Basis of the Function of Transcriptional Enhancers // Cells. 2020. Vol. 9. No. 7. p. 1620.

GOST all authors (up to 50) Copy

Ibragimov A. N., Bylino O. V., Shidlovskii Y. V. Molecular Basis of the Function of Transcriptional Enhancers // Cells. 2020. Vol. 9. No. 7. p. 1620.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3390/cells9071620

UR - https://doi.org/10.3390/cells9071620

TI - Molecular Basis of the Function of Transcriptional Enhancers

T2 - Cells

AU - Ibragimov, Airat N

AU - Bylino, Oleg V

AU - Shidlovskii, Y. V.

PY - 2020

DA - 2020/07/05

PB - MDPI

SP - 1620

IS - 7

VL - 9

PMID - 32635644

SN - 2073-4409

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2020_Ibragimov,

author = {Airat N Ibragimov and Oleg V Bylino and Y. V. Shidlovskii},

title = {Molecular Basis of the Function of Transcriptional Enhancers},

journal = {Cells},

year = {2020},

volume = {9},

publisher = {MDPI},

month = {jul},

url = {https://doi.org/10.3390/cells9071620},

number = {7},

pages = {1620},

doi = {10.3390/cells9071620}

}

MLA

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MLA Copy

Ibragimov, Airat N., et al. “Molecular Basis of the Function of Transcriptional Enhancers.” Cells, vol. 9, no. 7, Jul. 2020, p. 1620. https://doi.org/10.3390/cells9071620.

Publisher

MDPI

Journal

Cells

scimago Q1

wos Q2

SJR

1.670

CiteScore

10.5

Impact factor

5.2

ISSN

20734409 (Print, Electronic)

Labs

Laboratory for the Regulation of gene Expression in Development

Profiles