Open Access
Open access
MDPI
International Journal of Molecular Sciences
,  volume 23 ,  issue 15 ,  pages 8458

The Kv10.1 Channel: A Promising Target in Cancer

Publication type: Journal Article
Publication date: 2022-07-30
MDPI
scimago Q1
wos Q1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
DOI:  10.3390/ijms23158458
PubMed ID:  35955591
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract

Carcinogenesis is a multistage process involving the dysregulation of multiple genes, proteins, and pathways that make any normal cell acquire a cancer cell phenotype. Therefore, it is no surprise that numerous ion channels could be involved in this process. Since their discovery and subsequent cloning, ion channels have been established as therapeutic targets in excitable cell pathologies (e.g., cardiac arrhythmias or epilepsy); however, their involvement in non-excitable cell pathologies is relatively recent. Among all ion channels, the voltage-gated potassium channels Kv10.1 have been established as a promising target in cancer treatment due to their high expression in tumoral tissues compared to low levels in healthy tissues.

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GOST |
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GOST Copy
Luis E. et al. The Kv10.1 Channel: A Promising Target in Cancer // International Journal of Molecular Sciences. 2022. Vol. 23. No. 15. p. 8458.
GOST all authors (up to 50) Copy
Luis E., Anaya-Hernández A., León Sánchez P., Durán Pastén M. L. The Kv10.1 Channel: A Promising Target in Cancer // International Journal of Molecular Sciences. 2022. Vol. 23. No. 15. p. 8458.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/ijms23158458
UR - https://doi.org/10.3390/ijms23158458
TI - The Kv10.1 Channel: A Promising Target in Cancer
T2 - International Journal of Molecular Sciences
AU - Luis, Enoch
AU - Anaya-Hernández, Arely
AU - León Sánchez, Paulina
AU - Durán Pastén, María Luisa
PY - 2022
DA - 2022/07/30
PB - MDPI
SP - 8458
IS - 15
VL - 23
PMID - 35955591
SN - 1661-6596
SN - 1422-0067
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Luis,
author = {Enoch Luis and Arely Anaya-Hernández and Paulina León Sánchez and María Luisa Durán Pastén},
title = {The Kv10.1 Channel: A Promising Target in Cancer},
journal = {International Journal of Molecular Sciences},
year = {2022},
volume = {23},
publisher = {MDPI},
month = {jul},
url = {https://doi.org/10.3390/ijms23158458},
number = {15},
pages = {8458},
doi = {10.3390/ijms23158458}
}
MLA
Cite this
MLA Copy
Luis, Enoch, et al. “The Kv10.1 Channel: A Promising Target in Cancer.” International Journal of Molecular Sciences, vol. 23, no. 15, Jul. 2022, p. 8458. https://doi.org/10.3390/ijms23158458.