Open Access
International Journal of Molecular Sciences, volume 24, issue 3, pages 2937
Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications
Publication type: Journal Article
Publication date: 2023-02-02
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.6
ISSN: 16616596, 14220067
PubMed ID:
36769260
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
Piperidines are among the most important synthetic fragments for designing drugs and play a significant role in the pharmaceutical industry. Their derivatives are present in more than twenty classes of pharmaceuticals, as well as alkaloids. The current review summarizes recent scientific literature on intra- and intermolecular reactions leading to the formation of various piperidine derivatives: substituted piperidines, spiropiperidines, condensed piperidines, and piperidinones. Moreover, the pharmaceutical applications of synthetic and natural piperidines were covered, as well as the latest scientific advances in the discovery and biological evaluation of potential drugs containing piperidine moiety. This review is designed to help both novice researchers taking their first steps in this field and experienced scientists looking for suitable substrates for the synthesis of biologically active piperidines.
Citations by journals
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Angewandte Chemie
2 publications, 5.26%
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Angewandte Chemie - International Edition
2 publications, 5.26%
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ACS Omega
2 publications, 5.26%
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Organic and Biomolecular Chemistry
2 publications, 5.26%
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Nature Synthesis
1 publication, 2.63%
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RSC Advances
1 publication, 2.63%
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Polycyclic Aromatic Compounds
1 publication, 2.63%
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Journal of Chemical Health and Safety
1 publication, 2.63%
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Tetrahedron
1 publication, 2.63%
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Case Studies in Chemical and Environmental Engineering
1 publication, 2.63%
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Mendeleev Communications
1 publication, 2.63%
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Organic Chemistry Frontiers
1 publication, 2.63%
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Journal of the American Chemical Society
1 publication, 2.63%
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Chemistry of Heterocyclic Compounds
1 publication, 2.63%
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Chemistry - A European Journal
1 publication, 2.63%
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Catalysis Letters
1 publication, 2.63%
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Journal of Organic Chemistry
1 publication, 2.63%
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Bioorganic and Medicinal Chemistry
1 publication, 2.63%
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Phytochemistry
1 publication, 2.63%
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Chinese Chemical Letters
1 publication, 2.63%
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Biomedicine and Pharmacotherapy
1 publication, 2.63%
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ACS Applied Nano Materials
1 publication, 2.63%
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ACS Catalysis
1 publication, 2.63%
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Journal of Molecular Structure
1 publication, 2.63%
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Chemical Communications
1 publication, 2.63%
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Journal of Agricultural and Food Chemistry
1 publication, 2.63%
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European Journal of Medicinal Chemistry
1 publication, 2.63%
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Journal of Microbiology
1 publication, 2.63%
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Frontiers in Pharmacology
1 publication, 2.63%
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Citations by publishers
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Elsevier
9 publications, 23.68%
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American Chemical Society (ACS)
8 publications, 21.05%
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Wiley
6 publications, 15.79%
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Royal Society of Chemistry (RSC)
5 publications, 13.16%
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Springer Nature
4 publications, 10.53%
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Taylor & Francis
1 publication, 2.63%
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Han-Gug Misaengmul Hag-hoe/The Microbiological Society of Korea
1 publication, 2.63%
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Frontiers Media S.A.
1 publication, 2.63%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Frolov N. A., Vereshchagin A. N. Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications // International Journal of Molecular Sciences. 2023. Vol. 24. No. 3. p. 2937.
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Frolov N. A., Vereshchagin A. N. Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications // International Journal of Molecular Sciences. 2023. Vol. 24. No. 3. p. 2937.
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TY - JOUR
DO - 10.3390/ijms24032937
UR - https://doi.org/10.3390/ijms24032937
TI - Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications
T2 - International Journal of Molecular Sciences
AU - Frolov, Nikita A.
AU - Vereshchagin, Anatoly N.
PY - 2023
DA - 2023/02/02 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 2937
IS - 3
VL - 24
PMID - 36769260
SN - 1661-6596
SN - 1422-0067
ER -
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@article{2023_Frolov,
author = {Nikita A. Frolov and Anatoly N. Vereshchagin},
title = {Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications},
journal = {International Journal of Molecular Sciences},
year = {2023},
volume = {24},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {feb},
url = {https://doi.org/10.3390/ijms24032937},
number = {3},
pages = {2937},
doi = {10.3390/ijms24032937}
}
Cite this
MLA
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Frolov, Nikita A., and Anatoly N. Vereshchagin. “Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications.” International Journal of Molecular Sciences, vol. 24, no. 3, Feb. 2023, p. 2937. https://doi.org/10.3390/ijms24032937.