Open Access
Molecules, volume 19, issue 1, pages 306-315
Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase
Publication type: Journal Article
Publication date: 2013-12-27
PubMed ID:
24378969
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract
Nitrilimine generated by photolysis of diaryltetrazole in aqueous phase under mild conditions was trapped by nucleophiles including amines and thioalcohols. The representative products were characterized, while products with all 20 natural amino acids and a peptide were observed by MALDI-TOF mass spectroscopy. Competitive studies showed that this reaction also occurred in the presence of acrylamide. These results provided new information for understanding the potential side reactions when tetrazole-alkene pairs were used as a bioorthogonal reaction in labeling proteins and related studies in buffered systems.
Top-30
Journals
|
1
2
3
|
|
|
Chemistry - A European Journal
3 publications, 7.89%
|
|
|
Angewandte Chemie - International Edition
2 publications, 5.26%
|
|
|
Angewandte Chemie
2 publications, 5.26%
|
|
|
Chemical Reviews
2 publications, 5.26%
|
|
|
Methods in Enzymology
2 publications, 5.26%
|
|
|
ChemMedChem
2 publications, 5.26%
|
|
|
Gels
1 publication, 2.63%
|
|
|
Polymers
1 publication, 2.63%
|
|
|
Molecules
1 publication, 2.63%
|
|
|
Photochemical and Photobiological Sciences
1 publication, 2.63%
|
|
|
Bioorganic and Medicinal Chemistry
1 publication, 2.63%
|
|
|
Tetrahedron Letters
1 publication, 2.63%
|
|
|
Chem
1 publication, 2.63%
|
|
|
Polycyclic Aromatic Compounds
1 publication, 2.63%
|
|
|
Current Opinion in Chemical Biology
1 publication, 2.63%
|
|
|
Macromolecular Rapid Communications
1 publication, 2.63%
|
|
|
ChemPhotoChem
1 publication, 2.63%
|
|
|
ACS Sensors
1 publication, 2.63%
|
|
|
Journal of the American Chemical Society
1 publication, 2.63%
|
|
|
ACS Nano
1 publication, 2.63%
|
|
|
JACS Au
1 publication, 2.63%
|
|
|
Organic and Biomolecular Chemistry
1 publication, 2.63%
|
|
|
MedChemComm
1 publication, 2.63%
|
|
|
Chemical Communications
1 publication, 2.63%
|
|
|
Nanoscale Horizons
1 publication, 2.63%
|
|
|
Chemical Science
1 publication, 2.63%
|
|
|
Analytical and Bioanalytical Chemistry
1 publication, 2.63%
|
|
|
Organic Letters
1 publication, 2.63%
|
|
|
Russian Chemical Reviews
1 publication, 2.63%
|
|
|
1
2
3
|
Publishers
|
2
4
6
8
10
12
|
|
|
Wiley
11 publications, 28.95%
|
|
|
American Chemical Society (ACS)
7 publications, 18.42%
|
|
|
Elsevier
6 publications, 15.79%
|
|
|
Royal Society of Chemistry (RSC)
5 publications, 13.16%
|
|
|
MDPI
3 publications, 7.89%
|
|
|
Springer Nature
2 publications, 5.26%
|
|
|
Taylor & Francis
1 publication, 2.63%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 2.63%
|
|
|
2
4
6
8
10
12
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Zhang Y. et al. Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase // Molecules. 2013. Vol. 19. No. 1. pp. 306-315.
GOST all authors (up to 50)
Copy
Zhang Y., Liu W., Zhao Z. Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase // Molecules. 2013. Vol. 19. No. 1. pp. 306-315.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/molecules19010306
UR - https://doi.org/10.3390/molecules19010306
TI - Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase
T2 - Molecules
AU - Zhang, Yixin
AU - Liu, Wujun
AU - Zhao, Zongbao
PY - 2013
DA - 2013/12/27
PB - MDPI
SP - 306-315
IS - 1
VL - 19
PMID - 24378969
SN - 1420-3049
ER -
Cite this
BibTex
Copy
@article{2013_Zhang,
author = {Yixin Zhang and Wujun Liu and Zongbao Zhao},
title = {Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase},
journal = {Molecules},
year = {2013},
volume = {19},
publisher = {MDPI},
month = {dec},
url = {https://doi.org/10.3390/molecules19010306},
number = {1},
pages = {306--315},
doi = {10.3390/molecules19010306}
}
Cite this
MLA
Copy
Zhang, Yixin, et al. “Nucleophilic Trapping Nitrilimine Generated by Photolysis of Diaryltetrazole in Aqueous Phase.” Molecules, vol. 19, no. 1, Dec. 2013, pp. 306-315. https://doi.org/10.3390/molecules19010306.