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Molecules

, том 24 , издание 19 , страницы 3433

Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

Тип публикации: Journal Article

Дата публикации: 2019-09-21

MDPI

Molecules

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SJR: 0.865

CiteScore: 8.6

Impact factor: 4.6

ISSN: 14203049

DOI: 10.3390/molecules24193433

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PubMed ID: 31546633

Organic Chemistry

Drug Discovery

Physical and Theoretical Chemistry

Pharmaceutical Science

Molecular Medicine

Analytical Chemistry

Chemistry (miscellaneous)

Краткое описание

Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both Mycobacterium tuberculosis and several parasitic strains. As a result, a small structure activity relationship study was designed to further probe their activity and potential. Their synthesis and the results of the subsequent biological activity are reported herein.

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Molecules	Molecules, 2, 15.38% Molecules 2 публикации, 15.38%
Acta Naturae	Acta Naturae, 1, 7.69% Acta Naturae 1 публикация, 7.69%
Letters in Organic Chemistry	Letters in Organic Chemistry, 1, 7.69% Letters in Organic Chemistry 1 публикация, 7.69%
Frontiers in Chemistry	Frontiers in Chemistry, 1, 7.69% Frontiers in Chemistry 1 публикация, 7.69%
Computational and Theoretical Chemistry	Computational and Theoretical Chemistry, 1, 7.69% Computational and Theoretical Chemistry 1 публикация, 7.69%
Medicinal Research Reviews	Medicinal Research Reviews, 1, 7.69% Medicinal Research Reviews 1 публикация, 7.69%
ACS Infectious Diseases	ACS Infectious Diseases, 1, 7.69% ACS Infectious Diseases 1 публикация, 7.69%
Topics in Medicinal Chemistry	Topics in Medicinal Chemistry, 1, 7.69% Topics in Medicinal Chemistry 1 публикация, 7.69%
Proceedings of the National Academy of Sciences of Belarus Biological Series	Proceedings of the National Academy of Sciences of Belarus Biological Series, 1, 7.69% Proceedings of the National Academy of Sciences of Belarus Biological Series 1 публикация, 7.69%
Open Chemistry	Open Chemistry, 1, 7.69% Open Chemistry 1 публикация, 7.69%
Nucleosides, Nucleotides and Nucleic Acids	Nucleosides, Nucleotides and Nucleic Acids, 1, 7.69% Nucleosides, Nucleotides and Nucleic Acids 1 публикация, 7.69%
Journal of Organic Chemistry	Journal of Organic Chemistry, 1, 7.69% Journal of Organic Chemistry 1 публикация, 7.69%
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Acta Naturae Ltd	Acta Naturae Ltd, 1, 7.69% Acta Naturae Ltd 1 публикация, 7.69%
Bentham Science Publishers Ltd.	Bentham Science Publishers Ltd., 1, 7.69% Bentham Science Publishers Ltd. 1 публикация, 7.69%
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Khandazhinskaya A. et al. Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents // Molecules. 2019. Vol. 24. No. 19. p. 3433.

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Khandazhinskaya A., Matyugina E., Solyev P. N., Wilkinson M., Buckheit K., Buckheit R., Chernousova L., Smirnova T., Andreevskaya S., Alzahrani K., Natto M., Kochetkov S., De Koning H. P., Seley-Radtke K. L. Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents // Molecules. 2019. Vol. 24. No. 19. p. 3433.

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TY - JOUR

DO - 10.3390/molecules24193433

UR - https://doi.org/10.3390/molecules24193433

TI - Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

T2 - Molecules

AU - Khandazhinskaya, Anastasia

AU - Matyugina, Elena

AU - Solyev, Pavel N.

AU - Wilkinson, Maggie

AU - Buckheit, Karen

AU - Buckheit, Robert

AU - Chernousova, Larisa

AU - Smirnova, Tatiana

AU - Andreevskaya, Sofya

AU - Alzahrani, Khalid

AU - Natto, Manal

AU - Kochetkov, Sergey

AU - De Koning, Harry P.

AU - Seley-Radtke, Katherine L.

PY - 2019

DA - 2019/09/21

PB - MDPI

SP - 3433

IS - 19

VL - 24

PMID - 31546633

SN - 1420-3049

ER -

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@article{2019_Khandazhinskaya,

author = {Anastasia Khandazhinskaya and Elena Matyugina and Pavel N. Solyev and Maggie Wilkinson and Karen Buckheit and Robert Buckheit and Larisa Chernousova and Tatiana Smirnova and Sofya Andreevskaya and Khalid Alzahrani and Manal Natto and Sergey Kochetkov and Harry P. De Koning and Katherine L. Seley-Radtke},

title = {Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents},

journal = {Molecules},

year = {2019},

volume = {24},

publisher = {MDPI},

month = {sep},

url = {https://doi.org/10.3390/molecules24193433},

number = {19},

pages = {3433},

doi = {10.3390/molecules24193433}

}

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Khandazhinskaya, Anastasia, et al. “Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents.” Molecules, vol. 24, no. 19, Sep. 2019, p. 3433. https://doi.org/10.3390/molecules24193433.