Open Access
A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
Publication type: Journal Article
Publication date: 2020-04-20
PubMed ID:
32326131
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities, reported over the past one year (2019 to early 2020). This review highlights the trends in the use of nitrogen-based moieties in drug design and the development of different potent and competent candidates against various diseases.
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1.3k
Total citations:
1333
Citations from 2024:
644
(48.38%)
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GOST
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Kerru N. et al. A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications // Molecules. 2020. Vol. 25. No. 8. p. 1909.
GOST all authors (up to 50)
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Kerru N., Gummidi L., Maddila S., Gangu K. K., Jonnalagadda S. A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications // Molecules. 2020. Vol. 25. No. 8. p. 1909.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/molecules25081909
UR - https://doi.org/10.3390/molecules25081909
TI - A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
T2 - Molecules
AU - Kerru, Nagaraju
AU - Gummidi, Lalitha
AU - Maddila, Suresh
AU - Gangu, Kranthi Kumar
AU - Jonnalagadda, S.B.
PY - 2020
DA - 2020/04/20
PB - MDPI
SP - 1909
IS - 8
VL - 25
PMID - 32326131
SN - 1420-3049
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Kerru,
author = {Nagaraju Kerru and Lalitha Gummidi and Suresh Maddila and Kranthi Kumar Gangu and S.B. Jonnalagadda},
title = {A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications},
journal = {Molecules},
year = {2020},
volume = {25},
publisher = {MDPI},
month = {apr},
url = {https://doi.org/10.3390/molecules25081909},
number = {8},
pages = {1909},
doi = {10.3390/molecules25081909}
}
Cite this
MLA
Copy
Kerru, Nagaraju, et al. “A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications.” Molecules, vol. 25, no. 8, Apr. 2020, p. 1909. https://doi.org/10.3390/molecules25081909.