Open Access
Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
Тип публикации: Journal Article
Дата публикации: 2020-04-22
PubMed ID:
32331472
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Краткое описание
In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. Ascosphaera apis is a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity of cyclic synthetic peroxides against A. apis isolated from Bombus terrestris L. The peroxides exhibited high mycelium growth inhibition of A. apis up to 94–100% at concentration 30 mg/L. EC50 values were determined for the most active peroxides. Two peroxides showed higher antifungal activity against A. apis than the commercial fungicide Triadimefon. The studied peroxides did not reduce the ability of bumblebees to fly and did not lead to the death of bumblebees. A new field of application for peroxides was disclosed.
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Yaremenko I. A. et al. Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees // Molecules. 2020. Vol. 25. No. 8. p. 1954.
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Yaremenko I. A., Syromyatnikov M. Y., Radulov P. S., Belyakova Y. Yu., Fomenkov D. I., Popov V. N., Terent'ev A. O. Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees // Molecules. 2020. Vol. 25. No. 8. p. 1954.
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TY - JOUR
DO - 10.3390/molecules25081954
UR - https://www.mdpi.com/1420-3049/25/8/1954
TI - Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
T2 - Molecules
AU - Yaremenko, Ivan A
AU - Syromyatnikov, Mikhail Y
AU - Radulov, Peter S
AU - Belyakova, Yulia Yu
AU - Fomenkov, Dmitriy I
AU - Popov, V. N.
AU - Terent'ev, Alexander O.
PY - 2020
DA - 2020/04/22
PB - MDPI
SP - 1954
IS - 8
VL - 25
PMID - 32331472
SN - 1420-3049
ER -
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@article{2020_Yaremenko,
author = {Ivan A Yaremenko and Mikhail Y Syromyatnikov and Peter S Radulov and Yulia Yu Belyakova and Dmitriy I Fomenkov and V. N. Popov and Alexander O. Terent'ev},
title = {Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees},
journal = {Molecules},
year = {2020},
volume = {25},
publisher = {MDPI},
month = {apr},
url = {https://www.mdpi.com/1420-3049/25/8/1954},
number = {8},
pages = {1954},
doi = {10.3390/molecules25081954}
}
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MLA
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Yaremenko, Ivan A., et al. “Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees.” Molecules, vol. 25, no. 8, Apr. 2020, p. 1954. https://www.mdpi.com/1420-3049/25/8/1954.