Open Access
Pharmaceutics, volume 14, issue 4, pages 724
Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model
Permyakova Elizaveta S
1, 2
,
Konopatsky Anton
1
,
Ershov Konstantin I
2
,
Bakhareva Ksenia I
2
,
Sitnikova Natalya A
2
,
Publication type: Journal Article
Publication date: 2022-03-28
PubMed ID:
35456559
Pharmaceutical Science
Abstract
This study focused on the synthesis and characterization of pure curdlan–chitosan foams (CUR/CS), as well as foams containing Ag nanoparticles (CUR/CS/Ag), and their effect on the skin repair of diabetic mice (II type). The layer of antibacterial superabsorbent foam provides good oxygenation, prevents bacterial infection, and absorbs exudate, forming a soft gel (moist environment). These foams were prepared from a mixture of hydrolyzed curdlan and chitosan by lyophilization. To enhance the antibacterial properties, an AgNO3 solution was added to the curdlan/chitosan mixture during the polymerization and was then reduced by UV irradiation. The membranes were further investigated for their structure and composition using optical microscopy, scanning electron microscopy, energy-dispersive spectroscopy, FT-IR spectroscopy, and XPS analysis and modeling. In vivo tests demonstrated that CUR/CS/Ag significantly boosted the regeneration process compared with pure CUR/CS and the untreated control.
Citations by journals
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1
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3
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
3 publications, 33.33%
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Polymers
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Polymers
1 publication, 11.11%
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Journal of Composites Science
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Journal of Composites Science
1 publication, 11.11%
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Chemistry
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Chemistry
1 publication, 11.11%
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Current Opinion in Food Science
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Current Opinion in Food Science
1 publication, 11.11%
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Biomaterials Research
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Biomaterials Research
1 publication, 11.11%
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Pharmaceutics
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Pharmaceutics
1 publication, 11.11%
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1
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3
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Citations by publishers
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7
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
7 publications, 77.78%
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Elsevier
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Elsevier
1 publication, 11.11%
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Springer Nature
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Springer Nature
1 publication, 11.11%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Permyakova E. S. et al. Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model // Pharmaceutics. 2022. Vol. 14. No. 4. p. 724.
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Permyakova E. S., Konopatsky A., Ershov K. I., Bakhareva K. I., Sitnikova N. A., Shtansky D. V., Solovieva A. O., Manakhov A. Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model // Pharmaceutics. 2022. Vol. 14. No. 4. p. 724.
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TY - JOUR
DO - 10.3390/pharmaceutics14040724
UR - https://doi.org/10.3390%2Fpharmaceutics14040724
TI - Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model
T2 - Pharmaceutics
AU - Ershov, Konstantin I
AU - Bakhareva, Ksenia I
AU - Sitnikova, Natalya A
AU - Permyakova, Elizaveta S
AU - Konopatsky, Anton
AU - Shtansky, Dmitry V.
AU - Solovieva, Anastasiya O
AU - Manakhov, Anton
PY - 2022
DA - 2022/03/28 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 724
IS - 4
VL - 14
PMID - 35456559
SN - 1999-4923
ER -
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@article{2022_Permyakova,
author = {Konstantin I Ershov and Ksenia I Bakhareva and Natalya A Sitnikova and Elizaveta S Permyakova and Anton Konopatsky and Dmitry V. Shtansky and Anastasiya O Solovieva and Anton Manakhov},
title = {Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model},
journal = {Pharmaceutics},
year = {2022},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {mar},
url = {https://doi.org/10.3390%2Fpharmaceutics14040724},
number = {4},
pages = {724},
doi = {10.3390/pharmaceutics14040724}
}
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MLA
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Permyakova, Elizaveta S., et al. “Ag-Contained Superabsorbent Curdlan–Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model.” Pharmaceutics, vol. 14, no. 4, Mar. 2022, p. 724. https://doi.org/10.3390%2Fpharmaceutics14040724.