Open Access

Polymers

, volume 13 , issue 11 , pages 1684

Cyclodextrin Monomers and Polymers for Drug Activity Enhancement

Adrián Matencio ¹

Gjylije Hoti ¹

Yousef Monfared ¹

Azam Rezayat ^{1, 2}

Alberto Rubin Pedrazzo ¹

Fabrizio Caldera ¹

Francesco Trotta ¹

Hide authors affiliations Show authors affiliations: 2 affiliations

Dip. Di Chimica, Università di Torino, via P. Giuria 7, 10125 Torino, Italy |

Department of Chemistry, Faculty of Science, Lorestan University, Khorramabad, Iran |

Publication type: Journal Article

Publication date: 2021-05-21

MDPI

Polymers

scimago Q1

wos Q1

SJR: 0.918

CiteScore: 9.7

Impact factor: 4.9

ISSN: 20734360

DOI: 10.3390/polym13111684

Copy DOI

PubMed ID: 34064190

General Chemistry

Polymers and Plastics

Abstract

Cyclodextrins (CDs) and cyclodextrin (CD)-based polymers are well-known complexing agents. One of their distinctive features is to increase the quantity of a drug in a solution or improve its delivery. However, in certain instances, the activity of the solutions is increased not only due to the increase of the drug dose but also due to the drug complexation. Based on numerous studies reviewed, the drug appeared more active in a complex form. This review aims to summarize the performance of CDs and CD-based polymers as activity enhancers. Accordingly, the review is divided into two parts, i.e., the effect of CDs as active drugs and as enhancers in antimicrobials, antivirals, cardiovascular diseases, cancer, neuroprotective agents, and antioxidants.

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GOST |

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GOST Copy

Matencio A. et al. Cyclodextrin Monomers and Polymers for Drug Activity Enhancement // Polymers. 2021. Vol. 13. No. 11. p. 1684.

GOST all authors (up to 50) Copy

Matencio A., Hoti G., Monfared Y., Rezayat A., Rubin Pedrazzo A., Caldera F., Trotta F. Cyclodextrin Monomers and Polymers for Drug Activity Enhancement // Polymers. 2021. Vol. 13. No. 11. p. 1684.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3390/polym13111684

UR - https://doi.org/10.3390/polym13111684

TI - Cyclodextrin Monomers and Polymers for Drug Activity Enhancement

T2 - Polymers

AU - Matencio, Adrián

AU - Hoti, Gjylije

AU - Monfared, Yousef

AU - Rezayat, Azam

AU - Rubin Pedrazzo, Alberto

AU - Caldera, Fabrizio

AU - Trotta, Francesco

PY - 2021

DA - 2021/05/21

PB - MDPI

SP - 1684

IS - 11

VL - 13

PMID - 34064190

SN - 2073-4360

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2021_Matencio,

author = {Adrián Matencio and Gjylije Hoti and Yousef Monfared and Azam Rezayat and Alberto Rubin Pedrazzo and Fabrizio Caldera and Francesco Trotta},

title = {Cyclodextrin Monomers and Polymers for Drug Activity Enhancement},

journal = {Polymers},

year = {2021},

volume = {13},

publisher = {MDPI},

month = {may},

url = {https://doi.org/10.3390/polym13111684},

number = {11},

pages = {1684},

doi = {10.3390/polym13111684}

}

MLA

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MLA Copy

Matencio, Adrián, et al. “Cyclodextrin Monomers and Polymers for Drug Activity Enhancement.” Polymers, vol. 13, no. 11, May. 2021, p. 1684. https://doi.org/10.3390/polym13111684.

Publisher

MDPI

Journal

Polymers

scimago Q1

wos Q1

SJR

0.918

CiteScore

9.7

Impact factor

4.9

ISSN

20734360 (Electronic)