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Polymers, volume 14, issue 8, pages 1543

Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor

Publication typeJournal Article
Publication date2022-04-11
Journal: Polymers
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5
ISSN20734360
General Chemistry
Polymers and Plastics
Abstract

Electropolymerized neutral red, thionine, and aniline were used as part of hybrid nanocomposite conductive polymers, to create an amperometric reagent-less biosensor for glucose determination. The structure of the obtained polymers was studied using infrared (IR) spectroscopy and scanning electron microscopy. Electrochemical characteristics were studied by cyclic voltammetry and impedance spectroscopy. It was shown that, from the point of view of both the rate of electron transfer to the electrode, and the rate of interaction with the active center of glucose oxidase (GOx), the most promising is a new nanocomposite based on poly(neutral red) (pNR) and thermally expanded graphite (TEG). The sensor based on the created nanocomposite material is characterized by a sensitivity of 1000 ± 200 nA × dm3/mmol; the lower limit of the determined glucose concentrations is 0.006 mmol/L. The glucose biosensor based on this nanocomposite was characterized by a high correlation (R2 = 0.9828) with the results of determining the glucose content in human blood using the standard method. Statistical analysis did not reveal any deviations of the results obtained using this biosensor and the reference method. Therefore, the developed biosensor can be used as an alternative to the standard analysis method and as a prototype for creating sensitive and accurate glucometers, as well as biosensors to assess other metabolites.

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GOST Copy
Kuznetsova L. S. et al. Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor // Polymers. 2022. Vol. 14. No. 8. p. 1543.
GOST all authors (up to 50) Copy
Kuznetsova L. S., Arlyapov V. A., Kamanina O. A., Lantsova E. A., Tarasov S. E., Reshetilov A. N. Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor // Polymers. 2022. Vol. 14. No. 8. p. 1543.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/polym14081543
UR - https://doi.org/10.3390%2Fpolym14081543
TI - Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor
T2 - Polymers
AU - Kuznetsova, Lyubov S
AU - Kamanina, Olga A.
AU - Arlyapov, Vyacheslav A
AU - Lantsova, Elizaveta A
AU - Tarasov, Sergey E
AU - Reshetilov, A. N.
PY - 2022
DA - 2022/04/11 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 1543
IS - 8
VL - 14
PMID - 35458293
SN - 2073-4360
ER -
BibTex |
Cite this
BibTex Copy
@article{2022_Kuznetsova
author = {Lyubov S Kuznetsova and Olga A. Kamanina and Vyacheslav A Arlyapov and Elizaveta A Lantsova and Sergey E Tarasov and A. N. Reshetilov},
title = {Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor},
journal = {Polymers},
year = {2022},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {apr},
url = {https://doi.org/10.3390%2Fpolym14081543},
number = {8},
pages = {1543},
doi = {10.3390/polym14081543}
}
MLA
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MLA Copy
Kuznetsova, Lyubov S., et al. “Development of Nanocomposite Materials Based on Conductive Polymers for Using in Glucose Biosensor.” Polymers, vol. 14, no. 8, Apr. 2022, p. 1543. https://doi.org/10.3390%2Fpolym14081543.
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