Laboratory of biologically active compounds and biocomposites
Head of Laboratory
Arlyapov, Vyacheslav A
Publications
65
Citations
720
h-index
17
Authorization required.
The BASiB laboratory is engaged in the synthesis and study of the structure, properties and biological activity of new types of nitrogen-containing organic ionic compounds and biocomposite organosilicon materials for use in medicine, biotechnology and the chemical industry.
- Organic synthesis
- Various methods for the production of biomaterials/biocomposites, supramolecular complexes and sols of nanoparticles.
- Gas chromatography–mass spectrometry (GC–MS)
- UV spectroscopy
- IR spectroscopy
- Cyclic voltammetry
- NMR spectroscopy
- Mass spectrometry
- Scanning electron microscopy (SEM)
Vyacheslav Arlyapov
Head of Laboratory
Evgeniya Saverina
Leading researcher
Elizaveta Lantsova
Junior researcher
Roman Perchikov
Junior researcher
Lyubovy Kuznetsova
Junior researcher
Maxim Cheliukanov
Junior researcher
Research directions
Synthesis and identification of patterns of formation of biocomposite organosilicon materials
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Synthesis and identification of patterns of formation of biocomposite organosilicon materials of significant interest in the fields of ecology, biotechnology, and green chemical technology. The developed materials can be effectively used as biocatalysts. They can be used to create bioreactors, biosensors, biologics for the degradation of toxic compounds, implants, biofuel elements.
Synthesis of new generation antiseptics and disinfectants
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One of the main directions of the laboratory's work is the synthesis of new quaternary ammonium compounds (HH) based on available starting reagents. They have pronounced antibacterial, antifungal and antiviral effects, and are currently the basis of most antiseptics and disinfectants. However, there are more and more reports in the scientific literature about the occurrence of bacterial resistance to HH. This is an extremely alarming trend, as already in 2019, global mortality from diseases associated with microbial resistance exceeded mortality from HIV or malaria. Preparations developed in the Laboratory of biologically active compounds and biocomposites have shown high efficiency even against multi-resistant microorganisms. They are not inferior in efficiency to the most popular commercial analogues and retain their activity longer without developing microbial resistance.
Publications and patents
2023
—
2024
| Саверина Евгения Александровна
2023
—
2025
| Арляпов Вячеслав Алексеевич
2022
—
2023
| Каманина Ольга Александровна
Lab address
Тула, проспект Ленина, 92
Authorization required.