Open Access
Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems
Sergey Brezgin
1, 2, 3
,
Elena Volchkova
5
,
Ilya Gordeychuk
4, 7
,
Dieter Glebe
8
,
Dmitry Kostyushev
1, 3
,
Vladimir Chulanov
1, 3, 5
1
National Medical Research Center of Tuberculosis and Infectious Diseases, Ministry of Health, 127994 Moscow, Russia
|
6
Publication type: Journal Article
Publication date: 2021-07-15
PubMed ID:
34372578
Infectious Diseases
Virology
Abstract
Viral infections cause a variety of acute and chronic human diseases, sometimes resulting in small local outbreaks, or in some cases spreading across the globe and leading to global pandemics. Understanding and exploiting virus–host interactions is instrumental for identifying host factors involved in viral replication, developing effective antiviral agents, and mitigating the severity of virus-borne infectious diseases. The diversity of CRISPR systems and CRISPR-based tools enables the specific modulation of innate immune responses and has contributed impressively to the fields of virology and immunology in a very short time. In this review, we describe the most recent advances in the use of CRISPR systems for basic and translational studies of virus–host interactions.
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Metrics
18
Total citations:
18
Citations from 2024:
10
(55.56%)
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RIS |
BibTex |
MLA
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GOST
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Brezgin S. et al. Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems // Viruses. 2021. Vol. 13. No. 7. p. 1373.
GOST all authors (up to 50)
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Brezgin S., Kostyusheva A., Bayurova E., Volchkova E., Gegechkori V., Gordeychuk I., Glebe D., Kostyushev D., Chulanov V. Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems // Viruses. 2021. Vol. 13. No. 7. p. 1373.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/v13071373
UR - https://www.mdpi.com/1999-4915/13/7/1373
TI - Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems
T2 - Viruses
AU - Brezgin, Sergey
AU - Kostyusheva, Anastasiya
AU - Bayurova, Ekaterina
AU - Volchkova, Elena
AU - Gegechkori, Vladimir
AU - Gordeychuk, Ilya
AU - Glebe, Dieter
AU - Kostyushev, Dmitry
AU - Chulanov, Vladimir
PY - 2021
DA - 2021/07/15
PB - MDPI
SP - 1373
IS - 7
VL - 13
PMID - 34372578
SN - 1999-4915
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Brezgin,
author = {Sergey Brezgin and Anastasiya Kostyusheva and Ekaterina Bayurova and Elena Volchkova and Vladimir Gegechkori and Ilya Gordeychuk and Dieter Glebe and Dmitry Kostyushev and Vladimir Chulanov},
title = {Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems},
journal = {Viruses},
year = {2021},
volume = {13},
publisher = {MDPI},
month = {jul},
url = {https://www.mdpi.com/1999-4915/13/7/1373},
number = {7},
pages = {1373},
doi = {10.3390/v13071373}
}
Cite this
MLA
Copy
Brezgin, Sergey, et al. “Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems.” Viruses, vol. 13, no. 7, Jul. 2021, p. 1373. https://www.mdpi.com/1999-4915/13/7/1373.