Open Access
The chemistry of isoindole natural products
Publication type: Journal Article
Publication date: 2013-10-10
scimago Q2
wos Q3
SJR: 0.482
CiteScore: 3.8
Impact factor: 2.1
ISSN: 18605397
PubMed ID:
24204418
Organic Chemistry
Abstract
Summary This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type alkaloids. Concerning their biological activity, molecular structure and synthesis, we have limited this review to the most inspiring examples. Within different congeners, we have selected a few members and discussed the synthetic routes in more detail. The putative biosynthetic pathways of the presented isoindole alkaloids are described as well.
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340
Total citations:
340
Citations from 2024:
62
(18.23%)
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GOST
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Speck K., Magauer T. The chemistry of isoindole natural products // Beilstein Journal of Organic Chemistry. 2013. Vol. 9. pp. 2048-2078.
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Speck K., Magauer T. The chemistry of isoindole natural products // Beilstein Journal of Organic Chemistry. 2013. Vol. 9. pp. 2048-2078.
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TY - JOUR
DO - 10.3762/bjoc.9.243
UR - https://doi.org/10.3762/bjoc.9.243
TI - The chemistry of isoindole natural products
T2 - Beilstein Journal of Organic Chemistry
AU - Speck, Klaus
AU - Magauer, Thomas
PY - 2013
DA - 2013/10/10
PB - Beilstein-Institut
SP - 2048-2078
VL - 9
PMID - 24204418
SN - 1860-5397
ER -
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@article{2013_Speck,
author = {Klaus Speck and Thomas Magauer},
title = {The chemistry of isoindole natural products},
journal = {Beilstein Journal of Organic Chemistry},
year = {2013},
volume = {9},
publisher = {Beilstein-Institut},
month = {oct},
url = {https://doi.org/10.3762/bjoc.9.243},
pages = {2048--2078},
doi = {10.3762/bjoc.9.243}
}