Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation.
Publication type: Journal Article
Publication date: 1994-06-20
scimago Q3
wos Q2
SJR: 0.481
CiteScore: 4.8
Impact factor: 2.7
ISSN: 00218820, 18811469
PubMed ID:
8119861
Abstract
Penicillium sp. FO-2295, a water isolate, was found to produce a series of new anticoccidial compounds. Two active compounds, designated arohynapenes A and B, were isolated from the fermentation broth of the producing strain by solvent extration and preparative HPLC. Arohynapene A was deduced to be (2E,4E)-5-(5-hydroxy-2,6,8-trimethyl-5,6,7,8-tetrahydronaphtale ne)-2,4- pentadienoic acid, and arohynapene B was (2E,4E)-5-(2-hydroxymethyl-6,8-dimethyl-5,6,7,8-tetrahydronapht alene)-2,4- pentadienoic acid. Arohynapenes inhibited the growth of Eimeria tenella in an in vitro assay using BHK-21 cells as a host. No schizont in the cells was observed at concentrations ranging above 35.0 microM and 7.0 microM for arohynapenes A and B, respectively.
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Citations from 2024:
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(9.38%)
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GOST
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MASUMA R. et al. Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation. // Journal of Antibiotics. 1994. Vol. 47. No. 1. pp. 46-53.
GOST all authors (up to 50)
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MASUMA R., TABATA N., TOMODA H., HANEDA K., IWAI Y., OMURA S. Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation. // Journal of Antibiotics. 1994. Vol. 47. No. 1. pp. 46-53.
Cite this
RIS
Copy
TY - JOUR
DO - 10.7164/antibiotics.47.46
UR - https://doi.org/10.7164/antibiotics.47.46
TI - Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation.
T2 - Journal of Antibiotics
AU - MASUMA, R
AU - TABATA, N
AU - TOMODA, H
AU - HANEDA, K
AU - IWAI, Y
AU - OMURA, S
PY - 1994
DA - 1994/06/20
PB - Springer Nature
SP - 46-53
IS - 1
VL - 47
PMID - 8119861
SN - 0021-8820
SN - 1881-1469
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1994_MASUMA,
author = {R MASUMA and N TABATA and H TOMODA and K HANEDA and Y IWAI and S OMURA},
title = {Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation.},
journal = {Journal of Antibiotics},
year = {1994},
volume = {47},
publisher = {Springer Nature},
month = {jun},
url = {https://doi.org/10.7164/antibiotics.47.46},
number = {1},
pages = {46--53},
doi = {10.7164/antibiotics.47.46}
}
Cite this
MLA
Copy
MASUMA, R., et al. “Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation..” Journal of Antibiotics, vol. 47, no. 1, Jun. 1994, pp. 46-53. https://doi.org/10.7164/antibiotics.47.46.