volume 53 issue 11 pages 1247-1251

Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties.

Norihiro Kakinuma
Hiroki Iwai
Senji Takahashi
Kunikatsu Hamano
Tadashi YANAGISAWA
Koji Nagai
Koichi Tanaka
Ken’ichi Suzuki
Fumiko Kirikae
Teruo Kirikae
Akira Nakagawa
Publication typeJournal Article
Publication date2012-03-01
scimago Q3
wos Q2
SJR0.481
CiteScore4.8
Impact factor2.7
ISSN00218820, 18811469
Abstract
Quinolactacins A (1), B (2) and C (3), novel quinolone antibiotics have been found from the cultured broth of a fungal strain isolated from the larvae of the mulberry pyralid Margaronia pyloalis Welker). The fungal strain, EPF-6 was identified as Penicillium sp. from its morphological characteristics. Quinolactacins were obtained from the culture medium by solvent extraction and chromatographic purification. Compound 1 showed inhibitory activity against tumor necrosis factor (TNF) production induced by murine peritoneal macrophages and macrophage-like J774.1 cells stimulated with lipopolysaccharide (LPS).
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Kakinuma N. et al. Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties. // Journal of Antibiotics. 2012. Vol. 53. No. 11. pp. 1247-1251.
GOST all authors (up to 50) Copy
Kakinuma N., Iwai H., Takahashi S., Hamano K., YANAGISAWA T., Nagai K., Tanaka K., Suzuki K., Kirikae F., Kirikae T., Nakagawa A. Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties. // Journal of Antibiotics. 2012. Vol. 53. No. 11. pp. 1247-1251.
RIS |
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RIS Copy
TY - JOUR
DO - 10.7164/antibiotics.53.1247
UR - https://doi.org/10.7164/antibiotics.53.1247
TI - Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties.
T2 - Journal of Antibiotics
AU - Kakinuma, Norihiro
AU - Iwai, Hiroki
AU - Takahashi, Senji
AU - Hamano, Kunikatsu
AU - YANAGISAWA, Tadashi
AU - Nagai, Koji
AU - Tanaka, Koichi
AU - Suzuki, Ken’ichi
AU - Kirikae, Fumiko
AU - Kirikae, Teruo
AU - Nakagawa, Akira
PY - 2012
DA - 2012/03/01
PB - Springer Nature
SP - 1247-1251
IS - 11
VL - 53
PMID - 11213284
SN - 0021-8820
SN - 1881-1469
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2012_Kakinuma,
author = {Norihiro Kakinuma and Hiroki Iwai and Senji Takahashi and Kunikatsu Hamano and Tadashi YANAGISAWA and Koji Nagai and Koichi Tanaka and Ken’ichi Suzuki and Fumiko Kirikae and Teruo Kirikae and Akira Nakagawa},
title = {Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties.},
journal = {Journal of Antibiotics},
year = {2012},
volume = {53},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.7164/antibiotics.53.1247},
number = {11},
pages = {1247--1251},
doi = {10.7164/antibiotics.53.1247}
}
MLA
Cite this
MLA Copy
Kakinuma, Norihiro, et al. “Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties..” Journal of Antibiotics, vol. 53, no. 11, Mar. 2012, pp. 1247-1251. https://doi.org/10.7164/antibiotics.53.1247.