Organic Letters, volume 23, issue 17, pages 6977-6981
Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene
Publication type: Journal Article
Publication date: 2021-08-24
Journal:
Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.2
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A diversity-oriented and C2-selective synthesis of difluoroalkyl-substituted heteroarenes from three fragments, N-methoxyazinium salts, difluorocarbene, and electrophilic or radical reagents, is described. The reaction proceeds via the addition of difluorinated phosphorus ylide to in situ methylated heteroarene N-oxides, leading to phosphonium salts, which can undergo further transformations under basic or photoinduced conditions.
Citations by journals
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Organic Letters
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3 publications, 16.67%
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3 publications, 16.67%
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Angewandte Chemie - International Edition
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Angewandte Chemie - International Edition
3 publications, 16.67%
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Chemistry - A European Journal
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Chemistry - A European Journal
2 publications, 11.11%
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Chemical Communications
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2 publications, 11.11%
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Journal of the American Chemical Society
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1 publication, 5.56%
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Organic and Biomolecular Chemistry
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Organic and Biomolecular Chemistry
1 publication, 5.56%
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Science China Chemistry
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Science China Chemistry
1 publication, 5.56%
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Mendeleev Communications
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Mendeleev Communications
1 publication, 5.56%
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3
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Citations by publishers
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8
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Wiley
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Wiley
8 publications, 44.44%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
4 publications, 22.22%
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Royal Society of Chemistry (RSC)
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Royal Society of Chemistry (RSC)
3 publications, 16.67%
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Springer Nature
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Springer Nature
1 publication, 5.56%
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Elsevier
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Elsevier
1 publication, 5.56%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Trifonov A. L., Dilman A. D. Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene // Organic Letters. 2021. Vol. 23. No. 17. pp. 6977-6981.
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Trifonov A. L., Dilman A. D. Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene // Organic Letters. 2021. Vol. 23. No. 17. pp. 6977-6981.
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TY - JOUR
DO - 10.1021/acs.orglett.1c02603
UR - https://doi.org/10.1021%2Facs.orglett.1c02603
TI - Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene
T2 - Organic Letters
AU - Trifonov, Alexey L
AU - Dilman, Alexander D
PY - 2021
DA - 2021/08/24 00:00:00
PB - American Chemical Society (ACS)
SP - 6977-6981
IS - 17
VL - 23
SN - 1523-7060
SN - 1523-7052
ER -
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@article{2021_Trifonov,
author = {Alexey L Trifonov and Alexander D Dilman},
title = {Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene},
journal = {Organic Letters},
year = {2021},
volume = {23},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021%2Facs.orglett.1c02603},
number = {17},
pages = {6977--6981},
doi = {10.1021/acs.orglett.1c02603}
}
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MLA
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Trifonov, Alexey L., and Alexander D Dilman. “Synthesis of Difluoroalkylated Heteroarenes via Difluorocarbene.” Organic Letters, vol. 23, no. 17, Aug. 2021, pp. 6977-6981. https://doi.org/10.1021%2Facs.orglett.1c02603.
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