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Synthesis, structural characterization and cytotoxic activity of heterocyclic compounds containing the furoxan ring

Kulikov A.S., Larin A.A., Fershtat L.L., Anikina L.V., Pukhov S.A., Klochkov S.G., Struchkova M.I., Romanova A.A., Ananyev I.V., Makhova N.N.
Тип документаJournal Article
Дата публикации2017-08-07
Название журналаArkivoc
ИздательArkat USA
КвартильQ4
ISSN15517004, 15517012
  • Organic Chemistry
Краткое описание
A direct approach to the synthesis of previously unknown 1H-1,2,3-triazolylfuroxans, involving nucleophilic substitution of the nitro group in nitrofuroxans followed by catalytic [3+2] cycloaddition of intermediate azidofuroxans to 1,3-ketoesters, is reported. The scope of the triazolylfuroxans was additionally diversified through a number of transformations of the functional groups attached to the 1,2,3-triazole ring. The cytotoxic activity of the newly synthesized triazolylfuroxans and of previously reported hetarylfuroxans was studied. The NO-donor capability of selected synthesized hetarylfuroxans was measured by the Griess reaction using a spectrophotometric technique.
Цитируется в публикациях: 17
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1. Kulikov A.S. и др. Synthesis, structural characterization and cytotoxic activity of heterocyclic compounds containing the furoxan ring // Arkivoc. 2017. Т. 2017. № 3. С. 250–268.
RIS |
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TY - JOUR

DO - 10.24820/ark.5550190.p010.229

UR - http://dx.doi.org/10.24820/ark.5550190.p010.229

TI - Synthesis, structural characterization and cytotoxic activity of heterocyclic compounds containing the furoxan ring

T2 - Arkivoc

AU - Kulikov, Alexander S.

AU - Larin, Alexander A.

AU - Fershtat, Leonid L.

AU - Anikina, Lada V.

AU - Pukhov, Sergey A.

AU - Klochkov, Sergey G.

AU - Struchkova, Marina I.

AU - Romanova, Anna A.

AU - Ananyev, Ivan V.

AU - Makhova, Nina N.

PY - 2017

DA - 2017/08/07

PB - ARKAT USA, Inc.

SP - 250-268

IS - 3

VL - 2017

SN - 1551-7012

ER -

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@article{2017,

doi = {10.24820/ark.5550190.p010.229},

url = {https://doi.org/10.24820%2Fark.5550190.p010.229},

year = 2017,

month = {aug},

publisher = {{ARKAT} {USA}, Inc.},

volume = {2017},

number = {3},

pages = {250--268},

author = {Alexander S. Kulikov and Alexander A. Larin and Leonid L. Fershtat and Lada V. Anikina and Sergey A. Pukhov and Sergey G. Klochkov and Marina I. Struchkova and Anna A. Romanova and Ivan V. Ananyev and Nina N. Makhova},

editor = {Jacques Royer},

title = {Synthesis, structural characterization and cytotoxic activity of heterocyclic compounds containing the furoxan ring}

}

MLA
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Kulikov, Alexander S. et al. “Synthesis, Structural Characterization and Cytotoxic Activity of Heterocyclic Compounds Containing the Furoxan Ring.” Ed. Jacques Royer. Arkivoc 2017.3 (2017): 250–268. Crossref. Web.