Open Access
Open access

Egyptian Journal of Biological Pest Control

Springer Nature
Springer Nature
ISSN: 11101768, 25369342
SCImago
Q1
WOS
Q1
Impact factor
2.1
SJR
0.626
CiteScore
4.9
Categories
Agronomy and Crop Science
Insect Science
Ecology
Plant Science
Areas
Agricultural and Biological Sciences
Environmental Science
Years of issue
2008-2025
journal names
Egyptian Journal of Biological Pest Control
EGYPT J BIOL PEST CO
Publications
832
Citations
6 507
h-index
32
Top-3 citing journals
Plants
Plants (163 citations)
Insects
Insects (139 citations)
Top-3 organizations
Assiut University
Assiut University (13 publications)
Cairo University
Cairo University (12 publications)
King Abdulaziz University
King Abdulaziz University (8 publications)
Top-3 countries
Egypt (263 publications)
India (195 publications)
Turkey (84 publications)

Most cited in 5 years

Found 
from chars
Publications found: 497
The utility of animal models to inform the next generation of human space exploration
Duporge I., Pereira T., de Obeso S.C., Ross J.G., J. Lee S., G. Hindle A.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Abstract Animals have played a vital role in every stage of space exploration, from early sub-orbital flights to contemporary missions. New physiological and psychological challenges arise with plans to venture deeper into the solar system. Advances in chimeric and knockout animal models, along with genetic modification techniques have enhanced our ability to study the effects of microgravity in greater detail. However, increased investment in the purposeful design of habitats and payloads, as well as in AI-enhanced behavioral monitoring in orbit can better support the ethical and effective use of animals in deep space research.
Plyometric training increases thickness and volume of knee articular cartilage in mice
Chiaberge M., Thottappillil N., Liphardt A., Furlanetto A., Odell D., Wang C., Hope S., Smee S., Rehfus J., Niehoff A., Shelhamer M., Norman C., Philippon M.J., Huard J., James A.W., et. al.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Abstract Degeneration and thinning of articular cartilage lead to osteoarthritis and may result from reduced joint loading during e.g. bed rest or as a result of microgravity during space flight. Anabolic physical exercises for cartilage are not well studied to date. We built an experimental apparatus for plyometric training with mice to test potential benefits of jumping for articular cartilage. The exercise group (JUMP) performed jump training for 9 weeks and was compared with sedentary mice (control, CON) and hindlimb-suspended (HLS) mice (to simulate reduced loading) for the same duration. Knee cartilage was assessed via 3-dimensional reconstruction of micro-CT scans and histology. We observed significant thinning and volume reduction of articular cartilage at the medial tibial-femoral point of contact in the HLS group. Clustering of chondrocytes was present in HLS. By contrast, the JUMP group showed both cartilage thickening and volume increase. We observed a similar trend on trabecular bone thickness and volume. Our results show that plyometric training can stimulate cartilage thickness and volume in mice. This suggests further investigation of this mode of exercise as a countermeasure to prevent cartilage atrophy in disuse scenarios such as long duration spaceflight, and for patients at risk of developing osteoarthritis.
Validated space radiation exposure predictions from earth to mars during Artemis-I
Slaba T.C., Rahmanian S., George S., Laramore D., Norbury J.W., Werneth C.M., Zeitlin C.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Abstract Accurate characterization of space radiation exposure is critical to assess and communicate multiple health risks for crewmembers participating in future exploration missions. A combination of models and on-board instruments are utilized to meet this requirement. In this work, computational models are evaluated against spaceflight measurements taken within the International Space Station, the Orion spacecraft, the BioSentinel CubeSat, and on the Martian surface. All calculations and measurements cover the exact same time period defined by the Artemis-I mission, and all model calculations were performed blind—without prior knowledge of the measurements. The models are shown to accurately characterize the absorbed dose-rate in highly complex and diverse shielding configurations in locations from Earth to Mars.
Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight
Du Y., Han B., Biere K., Abdelmalek N., Shu X., Song C., Chen G., Li N., Tuschen M., Wu H., Sun S., Choukér A., Long M., Moser D.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Abstract Returning to the moon and traveling to Mars represent the main targets of human space exploration missions within the upcoming decades. Comparable to microgravity, partial gravity in these destinations is assumed to dysregulate immune functions, thereby threatening astronauts´ health. To investigate the impact of partial gravity on immune cell attachment to vessel endothelia, THP-1 cells and HUVEC cell layers were monitored in a flow chamber system during parabolic flight in lunar (0.16 g) or Martian (0.38 g) gravity. Focus was set on floating speed, cell adhesion, surface molecule expression and cytoskeletal reorganization under basal and TNF-induced inflammatory environment. Floating speed of THP-1 cells was increased in partial gravity, which was accompanied by a successively lower adhesion to the endothelial HUVEC cells. Expression levels of the adhesion markers Mac-1 on THP-1 cells as well as ICAM-1 on HUVECs were found elevated in lunar and Martian gravity, which was aggravated by TNF. Analysis of cytoskeletal organization in HUVECs revealed reduced intracellular F-actin microfilament networks and a stronger cell directionality with stress fiber alignment at cell borders in partial gravity, which was intensified by TNF. In summary, altered immune cell - endothelium interactions as quantified in partial gravity conditions show similarities to cellular behavior in microgravity. However, the different magnitudes of effects in dependence of gravitational level still need to be assessed in further investigations.
Simulated deep space exposure on seeds utilizing the MISSE flight facility
Richards J.T., Mortenson T.E., Spern C.J., Mousseau T.A., Gooden J.L., Spencer L.E., Khodadad C.L., Fischer J.A., Meyers A.D., Papenfuhs C.K., Buell J.G., Levine H.G., Dimapilis D.I., Zhang Y.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Abstract The MISSE-Seed project was designed to investigate the effects of space exposure on seed quality and storage. The project tested the Multipurpose Materials International Space Station Experiment—Flight Facility (MISSE-FF) hardware as a platform for exposing biological samples to the space environment outside the International Space Station (ISS). Furthermore, it evaluated the capability of a newly designed passive sample containment canister as a suitable exposure unit for biological samples for preserving their vigor while exposing to the space environment to study multi-stressor effects. The experiment was launched to the ISS on Northrup Grumman (NG)-15. The exposure lasted eight months outside the ISS in the MISSE-FF at the Zenith position. The specimens consisted of eleven seed varieties. Temperature dataloggers and thermoluminescent dosimeters were included in each container to record environmental data. We presented here the hardware and experimental design, environmental profiles, and seed survival from post-flight germination tests.
Hypergravity is more challenging than microgravity for the human sensorimotor system
Chomienne L., Sainton P., Sarlegna F.R., Bringoux L.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
The importance of gravity for human motor control is well established, but it remains unclear how the central nervous system accounts for gravitational changes to perform complex motor skills. We tested the hypothesis that microgravity and hypergravity have distinct effects on the neuromuscular control of reaching movements compared to normogravity. To test the influence of gravity levels on sensorimotor planning and control, participants (n = 9) had to reach toward visual targets during parabolic flights. Whole-body kinematics and muscular activity were adjusted in microgravity, allowing arm reaching to be as accurate as in normogravity. However, we observed in hypergravity a systematic undershooting, which likely resulted from a lack of reorganization of muscle activations. While new studies are necessary to clarify whether hypergravity impairs the internal model of limb dynamics, our findings provide new evidence that hypergravity creates a challenge that the human sensorimotor system is unable to solve in the short term.
Space exploration and risk of Parkinson’s disease: a perspective review
Ali N., Beheshti A., Hampikian G.
Q1
Springer Nature
npj Microgravity 2025 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Systemic mitochondrial dysfunction, dopamine loss, sustained structural changes in the basal ganglia including reduced tyrosine hydroxylase, and altered gait- these effects observed in space-flown animals and astronauts mirrors Parkinson’s disease (PD). Evidence of mitochondrial changes in space-flown human cells, examined through the lens of PD, suggests that spaceflight-induced PD-like molecular changes are important to monitor during deep space exploration. These changes, may potentially elevate the risk of PD in astronauts.
Aerospace medicine in China: advancements and perspectives
Wang A., Yang J., Tang S., Cui Y., Zhao J., Wang J., Li X., Zhao Y., Wang G., Du J.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
With the rapid growth of China’s space industry, long-term manned space missions face challenges from the complex space environment, posing risks to human health. Aerospace medicine, a key field, addresses these risks by researching the impacts of space on biochemical changes, cognitive abilities, and immune systems. This article reviews China’s aerospace medicine research, summarizing efforts from various institutions and offering insights for future developments in the field.
Hypothesis on the outflow of optic nerve cerebrospinal fluid in spaceflight associated neuro ocular syndrome
Hu Y., Lin Y., Cheng L., Xu Y., Zhang J., Zheng Z., Wang H., Yan M., Chen H.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Spaceflight-associated neuro-ocular syndrome (SANS) has been well documented in astronauts. However, its pathogenesis is not fully understood. New findings indicate the impaired outflow of the optic nerve cerebrospinal fluid may participate or contribute to some changes in SANS. In this perspective, we generated a hypothesis that the outflow of cerebrospinal fluid through the optic nerve sheath may be impaired under micro-gravity and then may potentially lead to SANS-related alterations.
An advanced light scattering apparatus for investigating soft matter onboard the International Space Station
Martinelli A., Buzzaccaro S., Galand Q., Behra J., Segers N., Leussink E., Dhillon Y.S., Maes D., Lutsko J., Piazza R., Cipelletti L.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Colloidal solids (COLIS) is a state-of-the-art light scattering setup developed for experiments onboard the International Space Station (ISS). COLIS allows for probing the structure and dynamics of soft matter systems on a wide range of length scales, from a few nm to tens of microns, and on time scales from 100 ns to tens of hours. In addition to conventional static and dynamic light scattering, COLIS includes depolarized dynamic light scattering, a small-angle camera, photon correlation imaging, and optical manipulation of thermosensitive samples through an auxiliary near-infrared laser beam, thereby providing a unique platform for probing soft matter systems. We demonstrate COLIS through ground tests on standard Brownian suspensions, and on protein, colloidal glasses, and gel systems similar to those to be used in future ISS experiments.
Comparative study of gravity effects in directional solidification of Al-3.5 wt.% Si and Al-10 wt.% Cu alloys
Zhang G., Luo X., Li Y., Liu S.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Directional solidification experiments of Al-3.5 wt.% Si and Al-10 wt.% Cu alloys were conducted under gravity and microgravity conditions using a 50-m-high drop tube. The solidification morphology of the two alloys is mainly columnar dendrites and equiaxed dendrites, respectively. The dendrite arm spacing (DAS), eutectic content, grain size, and compositional distribution of both alloys exhibit distinct characteristics under gravity and microgravity conditions. The study introduces an innovative perspective by taking solute density and its redistribution behavior into account when discussing the gravity effects during the directional solidification of alloys. The results indicate that the way gravity works on the solidification behavior of alloys depends strongly on the redistribution behavior and density of solute as well as crystallization modes, such as columnar grain or equiaxed grain. These findings are helpful in clarifying the coupling mechanism of gravity and relevant factors on the solidification of alloys, not only contributing to understanding the effect of gravity on solidification better but also offering valuable guidance for eliminating solidification segregation and producing high-performance alloys.
Sex-specific cardiovascular adaptations to simulated microgravity in Sprague-Dawley rats
Elsangeedy E., Yamaleyeva D.N., Edenhoffer N.P., Deak A., Soloshenko A., Ray J., Sun X., Shaltout O.H., Cruz-Diaz N., Westwood B., Kim-Shapiro D., Diz D.I., Soker S., Pulgar V.M., Ronca A., et. al.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Men and women have different cardiovascular responses to spaceflight; however, few studies have focused on direct comparisons between sexes. We investigated the mechanisms of aortic stiffening in socially and sexually mature 20-week-old male and female Sprague Dawley (SD) rats exposed to hindlimb unloading (HLU) for 14 days. Pulse wave velocity (PWV) was greater in the aortic arch of females after HLU versus control females (n = 6–8). HLU had no effect on aortic PWV in males (n = 5–6). Aortic α smooth muscle actin, myosin, collagen, elastin, and collagen-to-elastin ratio were not different in rats of either sex following HLU. The levels of G protein-coupled estrogen receptor (GPER) were lower in the aorta of SD females exposed to HLU compared with female controls but were not altered in males. HLU females also had lower aortic PPARγ, increased oxidative stress markers, and diastolic dysfunction compared with control females. GPER agonist G1 prevented the increase in PWV and 8-hydroxy-2’-deoxyguanosine without altering PPARγ or p47phox in HLU females (n = 4 in each group) suggesting that lower GPER may contribute to arterial stiffening in the setting of simulated microgravity. This study highlights sex-specific vascular adaptations to the state of simulated microgravity.
Impact of near continuous low dose rate neutron irradiation on pregnancy outcomes in mice
Steller J.G., Blue R.S., Ronca A.E., Goodspeed A., Powell T.L., Jansson T.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
The effects of galactic cosmic radiation on reproductive physiology remain largely unknown. We determined the impact of near-continuous low-dose-rate Californium-252 neutron irradiation (1 mGy/day) as a space-relevant analog on litter size and number of resorptions at embryonic day (E) 12.5 (n = 19 radiated dams, n = 20 controls) and litter size, number of resorptions, fetal growth, and placental signaling and transcriptome (RNA sequencing) at E18.5 (n = 21 radiated dams, n = 20 controls) in pregnant mice. A significantly increased early resorption rate and decreased placental weight were observed in irradiated mice. There were no statistically significant differences in litter size, fetal weight, length, or malformation rate between the groups. Near-continuous radiation had no significant effects on the mechanistic target of rapamycin (mTOR), endoplasmic reticulum stress or inflammatory signaling, rate of double-stranded DNA breaks, and had minimal effects on gene expression in the placenta. These data suggest that near-continuous, low-level galactic cosmic radiation has a limited impact on pregnancy outcomes.
Simulating microgravity with 60 days of 6 degree head-down tilt bed rest compromises sleep
Strauch L., von der Wiesche M., Noppe A., Mulder E., Rieger I., Aeschbach D., Elmenhorst E.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
AbstractAstronauts in space often experience sleep loss. In the AGBRESA (Artificial Gravity Bed Rest) study, we examined 24 participants (mean age ± SD, 33 ± 9 years) during two months of 6o head-down tilt (HDT) bed rest, which is a well-established spaceflight analogue. Polysomnography was recorded during baseline (BDC-9), HDT (nights 1, 8, 30 and 58) and recovery (R, nights 1 and 12). Mixed ANOVAs with post-hoc step-down Bonferroni adjustment indicated that compared to BDC-9, arousals were increased, while sleep duration, N3, and sleep efficiency were all decreased during HDT. Significant quadratic associations between sleep duration and quality with time into HDT did not indicate adaptive improvements during the course of HDT. While sleep duration recovered quickly after the end of bed rest, participants still displayed protracted sleep fragmentation. We conclude that physiological changes caused by exposure to microgravity may contribute to persistent sleep deficits experienced during real space missions.
Stressors affect human motor timing during spaceflight
Tian Y., Zhang Z., Jiang C., Chen D., Liu Z., Wei M., Wang C., Wei K.
Q1
Springer Nature
npj Microgravity 2024 citations by CoLab: 0
Open Access
Open access
PDF  |  Abstract
Crewed outer-space missions require adequate motor capacity among astronauts, whose sensorimotor system is disturbed by microgravity. Stressors other than microgravity, e.g., sleep loss, confinement, and high workload, characterize the living experience in space and potentially affect motor performance. However, the evidence of these stressors remains elusive. We recruited twelve taikonauts from the China Space Station to conduct a motor timing task that minimized the effect of microgravity on motor performance. Participants showed a remarkable increase in motor timing variance during spaceflight, compared to their pre- and post-flight performance and that of ground controls. Model-based analysis revealed that their timing deficits were driven by increased central noise instead of impaired motor execution. Our study provides evidence that nonspecific stressors can profoundly affect motor performance during spaceflight.

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Publishing countries

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Egypt, 263, 31.61%
India, 195, 23.44%
Turkey, 84, 10.1%
Pakistan, 71, 8.53%
Saudi Arabia, 70, 8.41%
China, 58, 6.97%
Iran, 37, 4.45%
Indonesia, 18, 2.16%
Tunisia, 17, 2.04%
Algeria, 15, 1.8%
USA, 14, 1.68%
Australia, 9, 1.08%
Mexico, 9, 1.08%
Vietnam, 8, 0.96%
Colombia, 8, 0.96%
Iraq, 6, 0.72%
Kenya, 6, 0.72%
Malaysia, 6, 0.72%
Philippines, 6, 0.72%
Morocco, 5, 0.6%
Nigeria, 5, 0.6%
Germany, 4, 0.48%
Belgium, 4, 0.48%
Syria, 4, 0.48%
Thailand, 4, 0.48%
Japan, 4, 0.48%
France, 3, 0.36%
Bangladesh, 3, 0.36%
Benin, 3, 0.36%
Brazil, 3, 0.36%
United Kingdom, 3, 0.36%
Greece, 3, 0.36%
Spain, 3, 0.36%
Canada, 3, 0.36%
Oman, 3, 0.36%
Rwanda, 3, 0.36%
Ethiopia, 3, 0.36%
Argentina, 2, 0.24%
Kyrgyzstan, 2, 0.24%
Cuba, 2, 0.24%
Poland, 2, 0.24%
Serbia, 2, 0.24%
Czech Republic, 2, 0.24%
Chile, 2, 0.24%
Switzerland, 2, 0.24%
South Africa, 2, 0.24%
Azerbaijan, 1, 0.12%
Afghanistan, 1, 0.12%
Botswana, 1, 0.12%
Bhutan, 1, 0.12%
Venezuela, 1, 0.12%
Guinea, 1, 0.12%
Denmark, 1, 0.12%
Israel, 1, 0.12%
Ireland, 1, 0.12%
Italy, 1, 0.12%
Yemen, 1, 0.12%
Cameroon, 1, 0.12%
North Korea, 1, 0.12%
Democratic Republic of the Congo, 1, 0.12%
Myanmar, 1, 0.12%
Norway, 1, 0.12%
UAE, 1, 0.12%
Palestine, 1, 0.12%
Paraguay, 1, 0.12%
Peru, 1, 0.12%
Slovakia, 1, 0.12%
Uruguay, 1, 0.12%
Ecuador, 1, 0.12%
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Egypt, 166, 26.06%
India, 164, 25.75%
Turkey, 56, 8.79%
Pakistan, 53, 8.32%
Saudi Arabia, 49, 7.69%
China, 45, 7.06%
Iran, 27, 4.24%
Indonesia, 18, 2.83%
Tunisia, 15, 2.35%
Algeria, 13, 2.04%
USA, 11, 1.73%
Australia, 9, 1.41%
Vietnam, 8, 1.26%
Mexico, 8, 1.26%
Colombia, 6, 0.94%
Philippines, 6, 0.94%
Morocco, 5, 0.78%
Nigeria, 5, 0.78%
Belgium, 4, 0.63%
Malaysia, 4, 0.63%
Thailand, 4, 0.63%
Japan, 4, 0.63%
Germany, 3, 0.47%
France, 3, 0.47%
Benin, 3, 0.47%
Brazil, 3, 0.47%
Greece, 3, 0.47%
Iraq, 3, 0.47%
Spain, 3, 0.47%
Kenya, 3, 0.47%
Syria, 3, 0.47%
Ethiopia, 3, 0.47%
United Kingdom, 2, 0.31%
Kyrgyzstan, 2, 0.31%
Cuba, 2, 0.31%
Poland, 2, 0.31%
Serbia, 2, 0.31%
Czech Republic, 2, 0.31%
Chile, 2, 0.31%
Switzerland, 2, 0.31%
South Africa, 2, 0.31%
Azerbaijan, 1, 0.16%
Argentina, 1, 0.16%
Afghanistan, 1, 0.16%
Bangladesh, 1, 0.16%
Botswana, 1, 0.16%
Bhutan, 1, 0.16%
Venezuela, 1, 0.16%
Guinea, 1, 0.16%
Denmark, 1, 0.16%
Israel, 1, 0.16%
Ireland, 1, 0.16%
Italy, 1, 0.16%
Yemen, 1, 0.16%
Cameroon, 1, 0.16%
Canada, 1, 0.16%
North Korea, 1, 0.16%
Democratic Republic of the Congo, 1, 0.16%
Myanmar, 1, 0.16%
Norway, 1, 0.16%
UAE, 1, 0.16%
Oman, 1, 0.16%
Paraguay, 1, 0.16%
Peru, 1, 0.16%
Uruguay, 1, 0.16%
Ecuador, 1, 0.16%
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