Laboratory of enzymology of nutrition

The main research work in the laboratory is carried out in the field of studying the role of certain nutrients in the regulation of the functional state of enzyme systems involved in defense and adaptation processes. At the same time, special attention is paid to the study of the influence of natural biologically active compounds on the activity of enzymes of various cell structures in order to elucidate the mechanisms of their action and to assess their effectiveness as substances necessary to maintain health and, to an even greater extent, to reduce the risk of a number of chronic diseases. An important direction of research carried out by the laboratory is the elucidation of enzyme mechanisms of the organism's defense against the impact of chemical food contaminants of natural and anthropogenic origin and the role of enzyme systems in ensuring the organism's resistance to their impact. The activity of enzymes of xenobiotic metabolism and antioxidant defense as the earliest and most sensitive markers of toxic effects is of primary importance. Along with fundamental research, the laboratory makes a significant contribution to the development of one of the most important areas of nutrition science - ensuring food safety. For the first time in our country, the research in the field of mycotoxicology initiated by the laboratory laid the foundation for the current system of control over mycotoxin contamination of food raw materials and food products in the Russian Federation. The laboratory staff developed the analytical and regulatory framework underlying this system.