Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers
Importance
The effectiveness of different approaches to dementia care is unknown.
Objective
To determine the effectiveness of health system–based, community-based dementia care, and usual care for persons with dementia and for caregiver outcomes.
Design, Setting, and Participants
Randomized clinical trial of community-dwelling persons living with dementia and their caregivers conducted at 4 sites in the US (enrollment June 2019-January 2023; final follow-up, August 2023).
Interventions
Participants were randomized 7:7:1 to health system–based care provided by an advanced practice dementia care specialist (n = 1016); community-based care provided by a social worker, nurse, or licensed therapist care consultant (n = 1016); or usual care (n = 144).
Main Outcomes and Measures
Primary outcomes were caregiver-reported Neuropsychiatric Inventory Questionnaire (NPI-Q) severity score for persons living with dementia (range, 0-36; higher scores, greater behavioral symptoms severity; minimal clinically important difference [MCID], 2.8-3.2) and Modified Caregiver Strain Index for caregivers (range, 0-26; higher scores, greater strain; MCID, 1.5-2.3). Three secondary outcomes included caregiver self-efficacy (range, 4-20; higher scores, more self-efficacy).
Results
Among 2176 dyads (individuals with dementia, mean age, 80.6 years; 58.4%, female; and 20.6%, Black or Hispanic; caregivers, mean age, 65.2 years; 75.8%, female; and 20.8% Black or Hispanic), primary outcomes were assessed for more than 99% of participants, and 1343 participants (62% of those enrolled and 91% still alive and had not withdrawn) completed the study through 18 months. No significant differences existed between the 2 treatments or between treatments vs usual care for the primary outcomes. Overall, the least squares means (LSMs) for NPI-Q scores were 9.8 for health system, 9.5 for community-based, and 10.1 for usual care. The difference between health system vs community-based care was 0.30 (97.5% CI, −0.18 to 0.78); health system vs usual care, −0.33 (97.5% CI, −1.32 to 0.67); and community-based vs usual care, −0.62 (97.5% CI, −1.61 to 0.37). The LSMs for the Modified Caregiver Strain Index were 10.7 for health system, 10.5 for community-based, and 10.6 for usual care. The difference between health system vs community-based care was 0.25 (97.5% CI, −0.16 to 0.66); health system vs usual care, 0.14 (97.5% CI, −0.70 to 0.99); and community-based vs usual care, −0.10 (97.5% CI, −0.94 to 0.74). Only the secondary outcome of caregiver self-efficacy was significantly higher for both treatments vs usual care but not between treatments: LSMs were 15.1 for health system, 15.2 for community-based, and 14.4 for usual care. The difference between health system vs community-based care was −0.16 (95% CI, −0.37 to 0.06); health system vs usual care, 0.70 (95% CI, 0.26-1.14); and community-based vs usual care, 0.85 (95% CI, 0.42 to 1.29).
Conclusions and Relevance
In this randomized trial of dementia care programs, no significant differences existed between health system–based and community-based care interventions nor between either active intervention or usual care regarding patient behavioral symptoms and caregiver strain.
Trial Registration
ClinicalTrials.gov Identifier:
Топ-30
Журналы
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JAMA - Journal of the American Medical Association
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Journal of the American Geriatrics Society
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JAMA Internal Medicine
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Journal of Alzheimer's Disease
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Deutsche Medizinische Wochenschrift
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Healthcare
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Public Policy & Aging Report
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JMIR Formative Research
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Research in gerontological nursing
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Издатели
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American Medical Association (AMA)
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Wiley
2 публикации, 16.67%
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SAGE
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Georg Thieme Verlag KG
1 публикация, 8.33%
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MDPI
1 публикация, 8.33%
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Oxford University Press
1 публикация, 8.33%
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JMIR Publications
1 публикация, 8.33%
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SLACK
1 публикация, 8.33%
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