том 27 , издание 10 , страницы 1365-1367

Solid‐Phase Synthesis of O‐Glycopeptide Sequences

Тип публикации: Journal Article

Дата публикации: 1988-10-01

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DOI: 10.1002/anie.198813651

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General Chemistry

Catalysis

Краткое описание

4-Alkoxybenzyl alcohol resins are suitable supports for the solid-phase synthesis of O-glycopeptides. This was shown by the syntheses of the hexapeptides 1 and 2 in 55 and 48% yield, respectively, based on the first amino acid to be coupled. β-Elimination, racemization, or glycoside cleavage were not observed.

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