The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies
Publication type: Journal Article
Publication date: 2009-01-12
scimago Q1
wos Q1
SJR: 5.550
CiteScore: 27.6
Impact factor: 16.9
ISSN: 14337851, 15213773
PubMed ID:
19090514
General Chemistry
Catalysis
Abstract
From the ocean: Ammosamides A (1) and B (2) were isolated from a marine-derived Streptomyces species collected in the Bahamas. The structures of these chlorinated tricyclic pyrroloquinoline alkaloids were solved using X-ray crystallographic techniques. Ammosamide A (1) was shown to contain an unusual thio-γ-lactam ring. Both metabolites show specific nanomolar cytotoxicity against selected cancer cell lines.
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173
Total citations:
173
Citations from 2025:
8
(4.63%)
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GOST
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Hughes C. C. et al. The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies // Angewandte Chemie - International Edition. 2009. Vol. 48. No. 4. pp. 725-727.
GOST all authors (up to 50)
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Hughes C. C., Macmillan J., Gaudêncio S. P., Jensen P., Fenical W. The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies // Angewandte Chemie - International Edition. 2009. Vol. 48. No. 4. pp. 725-727.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/anie.200804890
UR - https://doi.org/10.1002/anie.200804890
TI - The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies
T2 - Angewandte Chemie - International Edition
AU - Hughes, Chambers C.
AU - Macmillan, John
AU - Gaudêncio, Susana P.
AU - Jensen, Paul
AU - Fenical, W.
PY - 2009
DA - 2009/01/12
PB - Wiley
SP - 725-727
IS - 4
VL - 48
PMID - 19090514
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex (up to 50 authors)
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@article{2009_Hughes,
author = {Chambers C. Hughes and John Macmillan and Susana P. Gaudêncio and Paul Jensen and W. Fenical},
title = {The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies},
journal = {Angewandte Chemie - International Edition},
year = {2009},
volume = {48},
publisher = {Wiley},
month = {jan},
url = {https://doi.org/10.1002/anie.200804890},
number = {4},
pages = {725--727},
doi = {10.1002/anie.200804890}
}
Cite this
MLA
Copy
Hughes, Chambers C., et al. “The Ammosamides: Structures of Cell Cycle Modulators from a Marine-DerivedStreptomycesSpecies.” Angewandte Chemie - International Edition, vol. 48, no. 4, Jan. 2009, pp. 725-727. https://doi.org/10.1002/anie.200804890.