Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism
Тип публикации: Journal Article
Дата публикации: 2016-08-11
scimago Q1
wos Q2
БС2
SJR: 0.717
CiteScore: 6.7
Impact factor: 3.4
ISSN: 18607179, 18607187
PubMed ID:
27511289
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Molecular Medicine
General Pharmacology, Toxicology and Pharmaceutics
Краткое описание
A diverse library of 5‐thieno‐, 5‐oxo‐, and 5‐imino‐1,2,3‐dithiazole derivatives was synthesized and evaluated for efficacy against the feline immunodeficiency virus (FIV) as a model for HIV in cells. Several diverse compounds from this series displayed nanomolar activity and low toxicity, representing a potential new class of compounds for the treatment of FIV and HIV.
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ГОСТ
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Asquith C. R. M. et al. Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism // ChemMedChem. 2016. Vol. 11. No. 19. pp. 2119-2126.
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Asquith C. R. M., Konstantinova L. S., Laitinen T., Meli M. L., Poso A., Rakitin O. A., Hofmann-Lehmann R., HILTON S. Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism // ChemMedChem. 2016. Vol. 11. No. 19. pp. 2119-2126.
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TY - JOUR
DO - 10.1002/cmdc.201600260
UR - https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.201600260
TI - Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism
T2 - ChemMedChem
AU - Asquith, Christopher R M
AU - Konstantinova, Lidia S.
AU - Laitinen, Tuomo
AU - Meli, Marina L.
AU - Poso, Antti
AU - Rakitin, Oleg A.
AU - Hofmann-Lehmann, Regina
AU - HILTON, STEPHEN
PY - 2016
DA - 2016/08/11
PB - Wiley
SP - 2119-2126
IS - 19
VL - 11
PMID - 27511289
SN - 1860-7179
SN - 1860-7187
ER -
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BibTex (до 50 авторов)
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@article{2016_Asquith,
author = {Christopher R M Asquith and Lidia S. Konstantinova and Tuomo Laitinen and Marina L. Meli and Antti Poso and Oleg A. Rakitin and Regina Hofmann-Lehmann and STEPHEN HILTON},
title = {Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism},
journal = {ChemMedChem},
year = {2016},
volume = {11},
publisher = {Wiley},
month = {aug},
url = {https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.201600260},
number = {19},
pages = {2119--2126},
doi = {10.1002/cmdc.201600260}
}
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MLA
Скопировать
Asquith, Christopher R. M., et al. “Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism.” ChemMedChem, vol. 11, no. 19, Aug. 2016, pp. 2119-2126. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.201600260.
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