volume 17 issue 3 pages 509-534

Naphthoquinone pigments from sea urchins: chemistry and pharmacology

А. Е. Шиков 1
Olga N. Pozharitskaya 1
Anna S Krishtopina 1
Valery G Makarov 1
1
 
Saint-Petersburg Institute of Pharmacy, Kuzmolovo P 245, Russia
Publication typeJournal Article
Publication date2018-01-12
scimago Q1
wos Q1
SJR1.431
CiteScore16.3
Impact factor7.6
ISSN15687767, 1572980X
Plant Science
Biotechnology
Abstract
Due to their wide distribution, chemical diversity and scientifically confirmed pharmacological properties, sea urchin pigments have evoked renewed interest as a promising source material for the development of drugs that might be useful in clinical practice for the treatment of various human diseases. This review discusses advances in the chemistry, isolation, stability, and pharmacological and clinically proven activities of naphthoquinone pigments from sea urchins, as well as their safety uses. Recent decades have also witnessed studies concerning the anti-allergic, antidiabetic, antihypertensive, anti-inflammatory, antioxidant, cardioprotective, and hypocholesterolemic potential of pigments. Dimeric pigments are believed to be more active and largely responsible for observed pharmacological effects. The summarized data on observed pharmacological activity, coupled with a low toxicity profile, strongly support the view that naphthoquinone pigments could be potentially used in the development of agents possessing therapeutic benefits.
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GOST |
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GOST Copy
Шиков А. Е. et al. Naphthoquinone pigments from sea urchins: chemistry and pharmacology // Phytochemistry Reviews. 2018. Vol. 17. No. 3. pp. 509-534.
GOST all authors (up to 50) Copy
Шиков А. Е., Pozharitskaya O. N., Krishtopina A. S., Makarov V. G. Naphthoquinone pigments from sea urchins: chemistry and pharmacology // Phytochemistry Reviews. 2018. Vol. 17. No. 3. pp. 509-534.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s11101-018-9547-3
UR - https://doi.org/10.1007/s11101-018-9547-3
TI - Naphthoquinone pigments from sea urchins: chemistry and pharmacology
T2 - Phytochemistry Reviews
AU - Шиков, А. Е.
AU - Pozharitskaya, Olga N.
AU - Krishtopina, Anna S
AU - Makarov, Valery G
PY - 2018
DA - 2018/01/12
PB - Springer Nature
SP - 509-534
IS - 3
VL - 17
SN - 1568-7767
SN - 1572-980X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Шиков,
author = {А. Е. Шиков and Olga N. Pozharitskaya and Anna S Krishtopina and Valery G Makarov},
title = {Naphthoquinone pigments from sea urchins: chemistry and pharmacology},
journal = {Phytochemistry Reviews},
year = {2018},
volume = {17},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s11101-018-9547-3},
number = {3},
pages = {509--534},
doi = {10.1007/s11101-018-9547-3}
}
MLA
Cite this
MLA Copy
Шиков, А. Е., et al. “Naphthoquinone pigments from sea urchins: chemistry and pharmacology.” Phytochemistry Reviews, vol. 17, no. 3, Jan. 2018, pp. 509-534. https://doi.org/10.1007/s11101-018-9547-3.