The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells.
Publication type: Journal Article
Publication date: 1997-05-01
scimago Q1
wos Q1
SJR: 2.756
CiteScore: 13.9
Impact factor: 10.1
ISSN: 03043835, 18727980
PubMed ID:
9097981
Cancer Research
Oncology
Abstract
Cytotoxic effects of the Annonaceous acetogenin, bullatacin, were studied in multidrug-resistant (MDR) human mammary adenocarcinoma (MCF-7/Adr) cells vs. the parental non-resistant wild type (MCF-7/wt) cells. Bullatacin was effectively cytotoxic to the MCF-7/Adr cells while it was more cytostatic to the MCF-7/wt cells. ATP depletion is the mode of action of the Annonaceous acetogenins, and these agents offer a special advantage in the chemotherapeutic treatment of MDR tumors that have ATP-dependent mechanisms.
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121
Total citations:
121
Citations from 2024:
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(2.48%)
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GOST
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Oberlies N. H. et al. The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells. // Cancer Letters. 1997. Vol. 115. No. 1. pp. 73-79.
GOST all authors (up to 50)
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Oberlies N. H., Croy V. L., Harrison M. L., MCLAUGHLIN J. L. The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells. // Cancer Letters. 1997. Vol. 115. No. 1. pp. 73-79.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/S0304-3835(97)04716-2
UR - https://doi.org/10.1016/S0304-3835(97)04716-2
TI - The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells.
T2 - Cancer Letters
AU - Oberlies, Nicholas H.
AU - Croy, Vicki L
AU - Harrison, Marietta L.
AU - MCLAUGHLIN, Jerry L.
PY - 1997
DA - 1997/05/01
PB - Elsevier
SP - 73-79
IS - 1
VL - 115
PMID - 9097981
SN - 0304-3835
SN - 1872-7980
ER -
Cite this
BibTex (up to 50 authors)
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@article{1997_Oberlies,
author = {Nicholas H. Oberlies and Vicki L Croy and Marietta L. Harrison and Jerry L. MCLAUGHLIN},
title = {The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells.},
journal = {Cancer Letters},
year = {1997},
volume = {115},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/S0304-3835(97)04716-2},
number = {1},
pages = {73--79},
doi = {10.1016/S0304-3835(97)04716-2}
}
Cite this
MLA
Copy
Oberlies, Nicholas H., et al. “The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells..” Cancer Letters, vol. 115, no. 1, May. 1997, pp. 73-79. https://doi.org/10.1016/S0304-3835(97)04716-2.