Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents
Publication type: Journal Article
Publication date: 2019-07-01
scimago Q1
wos Q1
SJR: 0.786
CiteScore: 8.3
Impact factor: 4.7
ISSN: 00452068, 10902120
PubMed ID:
31077910
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Abstract
Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) and still remains one of the foremost fatal infectious diseases, infecting nearly a third of the worldwide population. The emergencies of multidrug-resistant and extensively drug-resistant tuberculosis (MDR and XDR-TB) prompt the efforts to deliver potent and novel anti-TB drugs. Research aimed at the development of new anti-TB drugs based on nitrofuran scaffold led to the identification of several candidates that were effective against actively growing as well as latent mycobacteria with unique modes of action. This review focuses on the recent advances in nitrofurans that could provide intriguing potential leads in the area of anti-TB drug discovery.
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28
Total citations:
28
Citations from 2025:
3
(10.71%)
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GOST
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Elsaman T., Mohamed M. S., Mohamed M. A. Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents // Bioorganic Chemistry. 2019. Vol. 88. p. 102969.
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Elsaman T., Mohamed M. S., Mohamed M. A. Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents // Bioorganic Chemistry. 2019. Vol. 88. p. 102969.
Cite this
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TY - JOUR
DO - 10.1016/j.bioorg.2019.102969
UR - https://doi.org/10.1016/j.bioorg.2019.102969
TI - Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents
T2 - Bioorganic Chemistry
AU - Elsaman, Tilal
AU - Mohamed, Malik Suliman
AU - Mohamed, Magdi A
PY - 2019
DA - 2019/07/01
PB - Elsevier
SP - 102969
VL - 88
PMID - 31077910
SN - 0045-2068
SN - 1090-2120
ER -
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BibTex (up to 50 authors)
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@article{2019_Elsaman,
author = {Tilal Elsaman and Malik Suliman Mohamed and Magdi A Mohamed},
title = {Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents},
journal = {Bioorganic Chemistry},
year = {2019},
volume = {88},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.bioorg.2019.102969},
pages = {102969},
doi = {10.1016/j.bioorg.2019.102969}
}