Biosensors and Bioelectronics

, volume 278 , pages 117308

Surface plasmon resonance biosensors and their medical applications

Tomáš Špringer ¹

Markéta Bocková ¹

Jiří Slabý ¹

Foozieh Sohrabi ¹

Magdalena Čapková ¹

Jiří Homola ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Institute of Photonics and Electronics of the Czech Academy of Sciences, Chaberská 1014/57, 182 51, Prague, Czech Republic |

Publication type: Journal Article

Publication date: 2025-06-01

Elsevier

Biosensors and Bioelectronics

scimago Q1

wos Q1

SJR: 2.007

CiteScore: 20.9

Impact factor: 10.5

ISSN: 09565663, 18734235

DOI: 10.1016/j.bios.2025.117308

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Abstract

Surface plasmon resonance (SPR) biosensors are an advanced optical biosensing technology that has been widely used in molecular biology for the investigation of biomolecular interactions and in bioanalytics for the detection of biological species. This work aims to review progress in the development of SPR biosensors for medical diagnostics, focusing mainly on advances in optical platforms and assays enabling analysis of complex biological matrices. Applications of SPR biosensors for the detection of medically relevant analytes, such as nucleic acids, proteins, exosomes, viruses, bacteria, and circulating tumor cells, are also reviewed. The detection performance of current SPR biosensors is discussed, and routes for improving performance and expanding applications of SPR biosensors in medical diagnostics are outlined.

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GOST Copy

Špringer T. et al. Surface plasmon resonance biosensors and their medical applications // Biosensors and Bioelectronics. 2025. Vol. 278. p. 117308.

GOST all authors (up to 50) Copy

Špringer T., Bocková M., Slabý J., Sohrabi F., Čapková M., Homola J. Surface plasmon resonance biosensors and their medical applications // Biosensors and Bioelectronics. 2025. Vol. 278. p. 117308.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.bios.2025.117308

UR - https://linkinghub.elsevier.com/retrieve/pii/S0956566325001824

TI - Surface plasmon resonance biosensors and their medical applications

T2 - Biosensors and Bioelectronics

AU - Špringer, Tomáš

AU - Bocková, Markéta

AU - Slabý, Jiří

AU - Sohrabi, Foozieh

AU - Čapková, Magdalena

AU - Homola, Jiří

PY - 2025

DA - 2025/06/01

PB - Elsevier

SP - 117308

VL - 278

SN - 0956-5663

SN - 1873-4235

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2025_Špringer,

author = {Tomáš Špringer and Markéta Bocková and Jiří Slabý and Foozieh Sohrabi and Magdalena Čapková and Jiří Homola},

title = {Surface plasmon resonance biosensors and their medical applications},

journal = {Biosensors and Bioelectronics},

year = {2025},

volume = {278},

publisher = {Elsevier},

month = {jun},

url = {https://linkinghub.elsevier.com/retrieve/pii/S0956566325001824},

pages = {117308},

doi = {10.1016/j.bios.2025.117308}

}

Publisher

Elsevier

Journal

Biosensors and Bioelectronics

scimago Q1

wos Q1

SJR

2.007

CiteScore

20.9

Impact factor

10.5

ISSN

09565663 (Print)

18734235 (Electronic)