Medical image segmentation and reconstruction of prostate tumor based on 3D AlexNet
Jun Chen
1
,
Zhechao Wan
2
,
Jiacheng Zhang
3
,
Wenhua Li
4
,
Yanbing Chen
5
,
Yuebing Li
6
,
Yue Duan
1
2
Department of Urology, Zhuji Central Hospital, No.98 Zhugong Road, Jiyang Street, Zhuji City, 311800, Zhejiang Province, China.
|
Publication type: Journal Article
Publication date: 2021-03-01
scimago Q1
wos Q1
SJR: 1.130
CiteScore: 11.1
Impact factor: 4.8
ISSN: 01692607, 18727565
PubMed ID:
33308904
Computer Science Applications
Software
Health Informatics
Abstract
Background Prostate cancer is a disease with a high incidence of tumors in men. Due to the long incubation time and insidious condition, early diagnosis is difficult; especially imaging diagnosis is more difficult. In actual clinical practice, the method of manual segmentation by medical experts is mainly used, which is time-consuming and labor-intensive and relies heavily on the experience and ability of medical experts. The rapid, accurate and repeatable segmentation of the prostate area is still a challenging problem. It is important to explore the automated segmentation of prostate images based on the 3D AlexNet network. Method Taking the medical image of prostate cancer as the entry point, the three-dimensional data is introduced into the deep learning convolutional neural network. This paper proposes a 3D AlexNet method for the automatic segmentation of prostate cancer magnetic resonance images, and the general network ResNet 50, Inception -V4 compares network performance. Results Based on the training samples of magnetic resonance images of 500 prostate cancer patients, a set of 3D AlexNet with simple structure and excellent performance was established through adaptive improvement on the basis of classic AlexNet. The accuracy rate was as high as 0.921, the specificity was 0.896, and the sensitivity It is 0.902 and the area under the receiver operating characteristic curve (AUC) is 0.964. The Mean Absolute Distance (MAD) between the segmentation result and the medical expert's gold standard is 0.356 mm, and the Hausdorff distance (HD) is 1.024 mm, the Dice similarity coefficient is 0.9768. Conclusion The improved 3D AlexNet can automatically complete the structured segmentation of prostate magnetic resonance images. Compared with traditional segmentation methods and depth segmentation methods, the performance of the 3D AlexNet network is superior in terms of training time and parameter amount, or network performance evaluation. Compared with the algorithm, it proves the effectiveness of this method.
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Chen J. et al. Medical image segmentation and reconstruction of prostate tumor based on 3D AlexNet // Computer Methods and Programs in Biomedicine. 2021. Vol. 200. p. 105878.
GOST all authors (up to 50)
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Chen J., Wan Z., Zhang J., Li W., Chen Y., Li Y., Duan Y. Medical image segmentation and reconstruction of prostate tumor based on 3D AlexNet // Computer Methods and Programs in Biomedicine. 2021. Vol. 200. p. 105878.
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TY - JOUR
DO - 10.1016/j.cmpb.2020.105878
UR - https://doi.org/10.1016/j.cmpb.2020.105878
TI - Medical image segmentation and reconstruction of prostate tumor based on 3D AlexNet
T2 - Computer Methods and Programs in Biomedicine
AU - Chen, Jun
AU - Wan, Zhechao
AU - Zhang, Jiacheng
AU - Li, Wenhua
AU - Chen, Yanbing
AU - Li, Yuebing
AU - Duan, Yue
PY - 2021
DA - 2021/03/01
PB - Elsevier
SP - 105878
VL - 200
PMID - 33308904
SN - 0169-2607
SN - 1872-7565
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Chen,
author = {Jun Chen and Zhechao Wan and Jiacheng Zhang and Wenhua Li and Yanbing Chen and Yuebing Li and Yue Duan},
title = {Medical image segmentation and reconstruction of prostate tumor based on 3D AlexNet},
journal = {Computer Methods and Programs in Biomedicine},
year = {2021},
volume = {200},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.cmpb.2020.105878},
pages = {105878},
doi = {10.1016/j.cmpb.2020.105878}
}