volume 76 issue 25 pages 2982-3021

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

Andrea Z Beaton
Jonathan Carapetis
Sumeet S. Chugh
Michael Criqui
Nicole Decleene
Gerry Fowkes
Nicholas Kassebaum
Walter Koroshetz
Awoke Misganaw Temesgen
Ali Mokdad
Glaucia Moraes de Oliveira
Catherine Otto
Mayowa Owolabi
Marissa Reitsma
Nancy Rigotti
Craig Sable
Saate Shakil
Karen Sliwa Hahnle
Benjamin Stark
Imad M. Tleyjeh
Liesl Zühlke
Christopher Murray
Gregory A. Roth
George A. Mensah
Catherine O Johnson
Giovanni Addolorato
Enrico Ammirati
Larry M. Baddour
Noël C. Barengo
Andrea Beaton
Emelia J. Benjamin
Catherine P Benziger
Aime Bonny
Michael Brauer
Marianne Brodmann
Thomas J Cahill
Jonathan R. Carapetis
Alberico L. Catapano
Sumeet Chugh
Leslie T. Cooper
Josef Coresh
Michael H. Criqui
Nicole K Decleene
Kim A. Eagle
Sophia Emmons-Bell
Valery L. Feigin
Joaquim Fernández Sola
F. Gerry R. Fowkes
Emmanuela Gakidou
Scott M. Grundy
Feng J. He
George Howard
Frank Hu
Lesley Inker
Ganesan Karthikeyan
Nicholas J. Kassebaum
Walter J. Koroshetz
Carl Lavie
Donald Lloyd-Jones
Hong S. Lu
Antonio Mirijello
Awoke T Misganaw
Ali H. Mokdad
Andrew E Moran
Paul Muntner
Jagat Narula
Bruce Neal
Mpiko Ntsekhe
Gláucia M M Oliveira
Catherine M. Otto
Mayowa O. Owolabi
Michael Pratt
Sanjay Rajagopalan
Marissa B Reitsma
Antonio Luiz P. Ribeiro
Nancy A. Rigotti
Anthony Rodgers
Craig A. Sable
Saate S. Shakil
Karen Sliwa
Benjamin A Stark
Johan Sundström
Patrick Timpel
Imad I Tleyjeh
Marco Valgimigli
Theo Vos
Paul K. Whelton
Magdi Yacoub
Liesl J Zuhlke
Mohsen Abbasi‐Kangevari
Alireza Abdi
Aidin Abedi
Victor Aboyans
Woldu A Abrha
Eman Abu Gharbieh
Abdelrahman I Abushouk
Dilaram Acharya
Tim Adair
Oladimeji M. Adebayo
Zanfina Ademi
Shailesh M Advani
Khashayar Afshari
Ashkan Afshin
Gina Agarwal
Pradyumna Agasthi
Sepideh Ahmadi
Muktar B Ahmed
Budi Aji
Yonas Akalu
Wuraola Akande-Sholabi
Addis Aklilu
Chisom J Akunna
Fares Alahdab
Ayman Al-Eyadhy
Khalid F. AlHabib
Sheikh M. Alif
Vahid Alipour
Syed M. Aljunid
François Alla
Amir Almasi-Hashiani
Sami Almustanyir
Rajaa M. Al-Raddadi
Adeladza K Amegah
Saeed Amini
Arya Aminorroaya
Hubert Amu
Dickson A Amugsi
Robert Ancuceanu
Deanna Anderlini
Tudorel Andrei
Catalina Liliana Andrei
Alireza Ansari Moghaddam
Zelalem A Anteneh
Ippazio Cosimo Antonazzo
Benny Antony
Razique Anwer
Lambert T. Appiah
Jalal Arabloo
Johan Ärnlöv
Kurnia D Artanti
Zerihun Ataro
MARCEL AUSLOOS
Leticia Avila Burgos
Asma T Awan
Mamaru A Awoke
Henok T Ayele
Muluken A Ayza
Samad Azari
Darshan B B
Nafiseh Baheiraei
Atif A Baig
Ahad Bakhtiari
Maciej Banach
Palash C Banik
Emerson A Baptista
Miguel A Barboza
Lingkan Barua
Sanjay Basu
Neeraj Bedi
Yannick Béjot
Derrick A. Bennett
Isabela M. Benseñor
Adam E. Berman
Yihienew M Bezabih
Akshaya S. Bhagavathula
Sonu Bhaskar
Krittika Bhattacharyya
Ali Bijani
Boris Bikbov
Mulugeta M Birhanu
Archith Boloor
Luisa C Brant
Hermann Brenner
Nikolay I Briko
Zahid A. Butt
Florentino Luciano Caetano Dos Santos
Leah E Cahill
Lucero Cahuana Hurtado
Luis A Cámera
Ismael R Campos Nonato
Carlos Cantu Brito
Josip Car
Juan J. Carrero
Felix Carvalho
Carlos A Castañeda Orjuela
Ferrán Catalá López
Ester Cerin
Jaykaran Charan
Vijay Kumar Chattu
Simiao Chen
Ken L Chin
Jee Young J Choi
Dinh-Toi Chu
Sheng-Chia Chung
Massimo Cirillo
Sean Coffey
Sara Conti
Vera M. Costa
David K. Cundiff
Omid Dadras
Baye Dagnew
Xiaochen Dai
Albertino A.M. Damasceno
Lalit Dandona
Rakhi Dandona
Kairat Davletov
Vanessa De La Cruz Góngora
Fernando P De La Hoz
Jan-Walter De Neve
Edgar Denova-Gutiérrez
Meseret Derbew Molla
Behailu T Derseh
Rupak Desai
Günther Deuschl
Samath D Dharmaratne
Meghnath Dhimal
Raja Ram Dhungana
Mostafa Dianatinasab
Daniel Díaz
Shirin Djalalinia
Klara Dokova
Abdel Douiri
Bruce B. Duncan
Andre R Duraes
Arielle W Eagan
Sanam Ebtehaj
Aziz Eftekhari
Sahar Eftekharzadeh
Michael Ekholuenetale
Nevine El nahas
Islam Y. Elgendy
Muhammed Elhadi
Shaimaa I El Jaafary
Sadaf Esteghamati
Atkilt E Etisso
Oghenowede Eyawo
Ibtihal Fadhil
Emerito Jose A Faraon
Pawan S Faris
Medhat Farwati
Farshad Farzadfar
Eduarda Fernandes
Carlota Fernandez Prendes
Pietro Ferrara
Irina Filip
Florian Fischer
David Flood
Takeshi Fukumoto
Mohamed M. Gad
Shilpa Gaidhane
Morsaleh Ganji
Jalaj Garg
Abadi K Gebre
Birhan G Gebregiorgis
Kidane Z Gebregzabiher
Gebreamlak G Gebremeskel
Lemma Getacher
Abera Getachew Obsa
Alireza Ghajar
Ahmad Ghashghaee
Nermin Ghith
Simona Giampaoli
Syed Amir Gilani
Paramjit S. Gill
Richard F. Gillum
Ekaterina V Glushkova
Elena V Gnedovskaya
Mahaveer Golechha
Kebebe B Gonfa
Amir Hossein Goudarzian
Alessandra C Goulart
Jenny S. Guadamuz
Avirup Guha
Yuming Guo
Rajeev Gupta
Vladimir Hachinski
Nima Hafezi-Nejad
Teklehaimanot G Haile
Randah R. Hamadeh
Samer Hamidi
Graeme J Hankey
Arief Hargono
Risky K Hartono
Maryam Hashemian
Abdiwahab Hashi
Shoaib Hassan
Hamid Y Hassen
Rasmus J Havmoeller
Simon I. Hay
Khezar Hayat
Golnaz Heidari
Claudiu Herteliu
Ramesh Holla
Mostafa Hosseini
Mehdi Hosseinzadeh
Mihaela Hostiuc
Sorin Hostiuc
Mowafa Househ
Junjie Huang
Ayesha Humayun
Ivo Iavicoli
Charles U Ibeneme
Segun E Ibitoye
Olayinka S Ilesanmi
Irena M Ilic
Milena D Ilic
Usman Iqbal
Seyed Sina N Irvani
Sheikh Mohammed Shariful Islam
Rakibul M. Islam
Hiroyasu Iso
Masao Iwagami
Vardhmaan Jain
Tahereh Javaheri
Sathish Kumar Jayapal
Shubha Jayaram
Ranil Jayawardena
Panniyammakal Jeemon
Ravi P Jha
Jost B. Jonas
Jitendra Jonnagaddala
Farahnaz Joukar
Jacek J Jozwiak
Mikk Jürisson
Ali Kabir
Tanvir Kahlon
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Rohollah Kalhor
Ashwin Kamath
Ibrahim Kamel
Himal Kandel
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Ayele Semachew Kasa
Patrick D. M. C. Katoto
Gbenga A Kayode
Yousef S Khader
Mohammad Khammarnia
Muhammad S. Khan
Md Nuruzzaman Khan
Maseer Khan
Ejaz A Khan
Khaled Khatab
Gulam M A Kibria
Yun-Jin Kim
Gyu Ri Kim
Ruth W Kimokoti
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Mika Kivimaki
Dhaval Kolte
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Vladimir A Korshunov
Sindhura Lakshmi Koulmane Laxminarayana
Ai Koyanagi
Kewal Krishan
Vijay Krishnamoorthy
Barthelemy Kuate Defo
Burcu Kucuk Bicer
Vaman Kulkarni
G. Anil Kumar
Nithin Kumar
Om P. Kurmi
Dian Kusuma
Gene F. Kwan
Carlo La Vecchia
Ben Lacey
Tea Lallukka
Qing Lan
Savita Lasrado
Zohra S. Lassi
Paolo Lauriola
Wayne R. Lawrence
Laxmaiah Avula
Kate E Legrand
Ming-Chieh Li
Bingyu Li Bingyu
Shanshan Li
Stephen S. Lim
Lee-Ling Lim
Hualiang Lin
Ziqiang Lin
Ro Ting Lin
Xuefeng Liu
Alan D. Lopez
Stefan Lorkowski
Paulo A Lotufo
Alessandra Lugo
Nirmal K M
Fabiana Madotto
Morteza Mahmoudi
Azeem Majeed
Reza Malekzadeh
Ahmad A. Malik
Abdullah A. Mamun
Navid Manafi
Mohammad Ali Mansournia
Lorenzo G. Mantovani
Santi Martini
Manu R Mathur
Giampiero Mazzaglia
Suresh Mehata
Man Mohan Mehndiratta
Toni Meier
Ritesh G. Menezes
Atte Meretoja
Tomislav Mestrovic
Bartosz Miazgowski
Tomasz Miazgowski
Irmina Maria Michalek
Ted R. Miller
Erkin M. Mirrakhimov
Hamed Mirzaei
Babak Moazen
Masoud Moghadaszadeh
Yousef Mohammad
Dara K Mohammad
Shafiu Mohammed
Mohammed A. Mohammed
Yaser Mokhayeri
Mariam Molokhia
Ahmed A Montasir
Ghobad Moradi
Rahmatollah Moradzadeh
Paula Moraga
Lidia Morawska
Ilais Moreno Velasquez
Jakub Morze
Sumaira Mubarik
Walter Muruet
Kamarul Imran Musa
Ahamarshan J Nagarajan
Mahdi Nalini
Vinay Nangia
Atta Abbas Naqvi
Sreenivas Narasimha Swamy
Bruno R. Nascimento
Vinod C Nayak
Javad Nazari
Milad Nazarzadeh
Ruxandra I Negoi
Sandhya Neupane Kandel
Huong L T Nguyen
Molly R. Nixon
Bo Norrving
Jean Jacques Noubiap
Brice E Nouthe
Christoph Nowak
Oluwakemi O Odukoya
Felix A. Ogbo
Andrew T Olagunju
Hans Orru
Alberto Ortiz
Samuel M Ostroff
Jagadish Rao Padubidri
Raffaele Palladino
Adrian Pana
Songhomitra Panda-Jonas
Utsav Parekh
Eun-Cheol Park
Mojtaba Parvizi
Fatemeh Pashazadeh Kan
Urvish K Patel
Mona Pathak
Rajan Paudel
Veincent Christian F Pepito
Arokiasamy Perianayagam
Norberto Perico
Hai Q Pham
Thomas Pilgrim
Michael A Piradov
Farhad Pishgar
Vivek Podder
Roman V Polibin
Akram Pourshams
Dimas R A Pribadi
Navid Rabiee
Mohammad Rabiee
Amir Radfar
Alireza Rafiei
Fakher Rahim
Vafa Rahimi-Movaghar
Mohammad Hifz Ur Rahman
Muhammad Aziz Rahman
AMIR MASOUD RAHMANI
Ivo Rakovac
Pradhum Ram
Sudha Ramalingam
Juwel Rana
Priyanga Ranasinghe
Sowmya J Rao
Priya Rathi
Lal Rawal
Wasiq F Rawasia
Reza Rawassizadeh
Giuseppe Remuzzi
Andre M N Renzaho
Aziz Rezapour
Seyed Mohammad Riahi
Ross L Roberts‐Thomson
Leonardo Roever
Peter Rohloff
Michele Romoli
Gholamreza Roshandel
Godfrey M Rwegerera
Seyedmohammad Saadatagah
Maha M Saber Ayad
Siamak Sabour
Simona Sacco
Masoumeh Sadeghi
Sahar Saeedi Moghaddam
Saeed Safari
Amirhossein Sahebkar
Sana Salehi
Hamideh Salimzadeh
Mehrnoosh Samaei
Abdallah M Samy
Itamar S. Santos
Milena M Santric Milicevic
Nizal Sarrafzadegan
Arash Sarveazad
Sathish Thirunavukkarasu
Monika Sawhney
Mete Saylan
Maria I Schmidt
Aletta E Schutte
Subramanian Senthilkumaran
Sadaf G. Sepanlou
Feng Sha
Saeed Shahabi
Izza Shahid
Masood A. Shaikh
Mahdi Shamali
Morteza SHAMSIZADEH
Md Shajedur Rahman Shawon
Aziz Sheikh
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Min-Jeong Shin
Jae Il Shin
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Soraya Siabani
Tariq J Siddiqi
Diego A.S. Silva
Jasvinder A Singh
Ambrish Singh Mtech
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Anna A Skryabina
Amin Soheili
Emma E Spurlock
Leo Stockfelt
Stefan Stortecky
Saverio Stranges
Rizwan Suliankatchi Abdulkader
Hooman Tadbiri
Eyayou G Tadesse
Degena B Tadesse
Masih Tajdini
Md Tariqujjaman
Berhane F Teklehaimanot
Mohamad-Hani Temsah
Ayenew K Tesema
Bhaskar Thakur
Kavumpurathu R Thankappan
Rekha Thapar
Amanda G Thrift
Binod Timalsina
Marcello Tonelli
Mathilde Touvier
Marcos R Tovani Palone
Avnish Tripathi
Jaya P Tripathy
Thomas C Truelsen
Guesh M Tsegay
Gebiyaw W Tsegaye
Nikolaos Tsilimparis
Biruk S Tusa
Stefanos Tyrovolas
Krishna Kishore Umapathi
Brigid Unim
Unnikrishnan Bhaskaran
Muhammad S Usman
Muthiah Vaduganathan
Pascual R Valdez
TOMMI J. VASANKARI
Diana Z Velazquez
Narayanaswamy Venketasubramanian
Giang T Vu
Isidora S. Vujcic
Yasir Waheed
Yanzhong Wang
Wang Fang
Jingkai Wei
ROBERT G. WEINTRAUB
Abrha H Weldemariam
Ronny Westerman
Andrea S. Winkler
Charles S. Wiysonge
Charles D.A. Wolfe
Befikadu Legesse Wubishet
Gelin Xu
Ali Yadollahpour
Kazumasa Yamagishi
Lijing L. Yan
Srikanth Yandrapalli
Yuichiro Yano
Hiroshi Yatsuya
Tomas Y Yeheyis
Yigizie Yeshaw
Christopher S. Yilgwan
Naohiro Yonemoto
Chuanhua Yu
Hasan Yusefzadeh
Zachariah Geevar
Sojib Bin Zaman
Muhammed S Zaman
Maryam Zamanian
Ramin Zand
Alireza Zandifar
Afshin Zarghi
Mikhail S Zastrozhin
Anasthasia Zastrozhina
Zhi-Jiang Zhang
Yunquan Zhang
Wangjian Zhang
Chenwen Zhong
Zhiyong Zou
Yves Miel H Zuniga
Christopher J. L. Murray
Valentin Fuster
Publication typeJournal Article
Publication date2020-12-10
scimago Q1
wos Q1
SJR9.015
CiteScore35.1
Impact factor22.3
ISSN07351097, 15583597
Cardiology and Cardiovascular Medicine
Abstract
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.
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Beaton A. Z. et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 // Journal of the American College of Cardiology. 2020. Vol. 76. No. 25. pp. 2982-3021.
GOST all authors (up to 50) Copy
Beaton A. Z. et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 // Journal of the American College of Cardiology. 2020. Vol. 76. No. 25. pp. 2982-3021.
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@article{2020_Beaton,
author = {Andrea Z Beaton and Jonathan Carapetis and Sumeet S. Chugh and Michael Criqui and Nicole Decleene and Gerry Fowkes and Nicholas Kassebaum and Walter Koroshetz and Awoke Misganaw Temesgen and Ali Mokdad and Glaucia Moraes de Oliveira and Catherine Otto and Mayowa Owolabi and Marissa Reitsma and Nancy Rigotti and Craig Sable and Saate Shakil and Karen Sliwa Hahnle and Benjamin Stark and Imad M. Tleyjeh and Liesl Zühlke and Christopher Murray and Gregory A. Roth and George A. Mensah and Catherine O Johnson and Giovanni Addolorato and Enrico Ammirati and Larry M. Baddour and Noël C. Barengo and Andrea Beaton and Emelia J. Benjamin and Catherine P Benziger and Aime Bonny and Michael Brauer and Marianne Brodmann and Thomas J Cahill and Jonathan R. Carapetis and Alberico L. Catapano and Sumeet Chugh and Leslie T. Cooper and Josef Coresh and Michael H. Criqui and Nicole K Decleene and Kim A. Eagle and Sophia Emmons-Bell and Valery L. Feigin and Joaquim Fernández Sola and F. Gerry R. Fowkes and Emmanuela Gakidou and Scott M. Grundy and others},
title = {Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019},
journal = {Journal of the American College of Cardiology},
year = {2020},
volume = {76},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.jacc.2020.11.010},
number = {25},
pages = {2982--3021},
doi = {10.1016/j.jacc.2020.11.010}
}
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Beaton, Andrea Z., et al. “Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019.” Journal of the American College of Cardiology, vol. 76, no. 25, Dec. 2020, pp. 2982-3021. https://doi.org/10.1016/j.jacc.2020.11.010.
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