volume 18 pages 54-59

Methylcellulose films partially crosslinked by iron compounds for medical applications

Publication typeJournal Article
Publication date2019-03-01
scimago Q1
wos Q2
SJR0.788
CiteScore5.8
Impact factor4.5
ISSN23524928
Materials Chemistry
General Materials Science
Mechanics of Materials
Abstract
Abstract Methylcellulose (MC) is now widely used in medicine to fill defects of damaged tissues. A new method is proposed to improve the stability of MC-based materials in aqueous media using non-toxic reagents. MC–alginate blend films are crosslinked by iron(II) and iron(III) ions using different iron salts. The resulting films are stable in physiological solution for about 14 days. Mechanical tests of the dried films show an increase in the Young's modulus with iron concentration in solutions. Mossbauer spectroscopy data show that the films contain Fe3+ ions alone irrespective of whether chlorides of Fe2+ or Fe3+ are applied as crosslinking agents. The use of ascorbic acid as a complexing agent prevents Fe2+ from oxidation. The obtained materials are stable for at least half a year. The resulting films facilitate the growth of human fibroblasts on their surface.
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GOST Copy
Fadeeva I. V. et al. Methylcellulose films partially crosslinked by iron compounds for medical applications // Materials Today Communications. 2019. Vol. 18. pp. 54-59.
GOST all authors (up to 50) Copy
Fadeeva I. V., Trofimchuk E., Dedushenko S. K., Fomin A. S., Davydova G. A., Selezneva I. I., Perfiliev Y. D., Barinov S. Methylcellulose films partially crosslinked by iron compounds for medical applications // Materials Today Communications. 2019. Vol. 18. pp. 54-59.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mtcomm.2018.10.008
UR - https://linkinghub.elsevier.com/retrieve/pii/S2352492818302125
TI - Methylcellulose films partially crosslinked by iron compounds for medical applications
T2 - Materials Today Communications
AU - Fadeeva, Inna V
AU - Trofimchuk, Elena
AU - Dedushenko, Sergey K
AU - Fomin, A. S.
AU - Davydova, Galina A
AU - Selezneva, Irina I.
AU - Perfiliev, Yuri D
AU - Barinov, S.M.
PY - 2019
DA - 2019/03/01
PB - Elsevier
SP - 54-59
VL - 18
SN - 2352-4928
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Fadeeva,
author = {Inna V Fadeeva and Elena Trofimchuk and Sergey K Dedushenko and A. S. Fomin and Galina A Davydova and Irina I. Selezneva and Yuri D Perfiliev and S.M. Barinov},
title = {Methylcellulose films partially crosslinked by iron compounds for medical applications},
journal = {Materials Today Communications},
year = {2019},
volume = {18},
publisher = {Elsevier},
month = {mar},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2352492818302125},
pages = {54--59},
doi = {10.1016/j.mtcomm.2018.10.008}
}