Tetrahedron

, volume 65 , issue 5 , pages 1033-1039

New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp.

Lin Du ^{1, 2}

Dehai Li ^{1, 2}

Tianjiao Zhu ^{1, 2}

Shengxin Cai ^{1, 2}

Fengping Wang ³

Xiang-sheng Xiao ³

Qianqun Gu ^{1, 2}

Hide authors affiliations Show authors affiliations: 3 affiliations

Key Laboratory of Marine Drugs, Chinese Ministry of Education

Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, PR China |

Key Laboratory of Marine Biogenetic Resources, The Third Institute of Oceanography, The State Oceanic Administration, Xiamen, PR China |

Publication type: Journal Article

Publication date: 2009-01-01

Elsevier

Tetrahedron

scimago Q3

wos Q2

SJR: 0.426

CiteScore: 4.1

Impact factor: 2.2

ISSN: 00404020, 14645416

DOI: 10.1016/j.tet.2008.11.078

Copy DOI

Organic Chemistry

Drug Discovery

Biochemistry

Abstract

Four new alkaloids, including two new meleagrin analogs, meleagrins B (2) and C (3), and two new diketopiperazines, roquefortines F (5) and G (6), together with six new diterpenes, conidiogenones B–G (7–12), were isolated from a deep ocean sediment derived fungus Penicillium sp. The structures and stereochemistry of the new compounds were elucidated by spectroscopic methods. The cytotoxicity of the new compounds against the HL-60, A-549, BEL-7402, and MOLT-4 cell lines was evaluated.

Found

1 citation

Yurchenko Anton

🥼

PhD in Chemistry

67 publications, 839 citations, 52 reviews

h-index: 17

G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences

1 citation

Popov Roman

🥼 🤝

116 publications, 1 149 citations

h-index: 17

G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences

1 citation

Khmel Olga

4 publications, 34 citations

h-index: 3

Far Eastern Federal University

G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences

1 citation

Yurchenko Ekaterina

🥼 🤝

PhD in Biological/biomedical sciences

91 publications, 966 citations, 16 reviews

h-index: 18

G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences

Research interests

Biologically active low molecular weight compounds

Bioorganic chemistry

Cell culture

Chemistry of natural compounds

Secondary metabolites

1 citation

Chingizova Ekaterina

PhD

80 publications, 680 citations

h-index: 14

G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences

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156

Cite this

GOST |

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GOST Copy

Du L. et al. New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp. // Tetrahedron. 2009. Vol. 65. No. 5. pp. 1033-1039.

GOST all authors (up to 50) Copy

Du L., Li D., Zhu T., Cai S., Wang F., Xiao X., Gu Q. New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp. // Tetrahedron. 2009. Vol. 65. No. 5. pp. 1033-1039.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.tet.2008.11.078

UR - https://doi.org/10.1016/j.tet.2008.11.078

TI - New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp.

T2 - Tetrahedron

AU - Du, Lin

AU - Li, Dehai

AU - Zhu, Tianjiao

AU - Cai, Shengxin

AU - Wang, Fengping

AU - Xiao, Xiang-sheng

AU - Gu, Qianqun

PY - 2009

DA - 2009/01/01

PB - Elsevier

SP - 1033-1039

IS - 5

VL - 65

SN - 0040-4020

SN - 1464-5416

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2009_Du,

author = {Lin Du and Dehai Li and Tianjiao Zhu and Shengxin Cai and Fengping Wang and Xiang-sheng Xiao and Qianqun Gu},

title = {New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp.},

journal = {Tetrahedron},

year = {2009},

volume = {65},

publisher = {Elsevier},

month = {jan},

url = {https://doi.org/10.1016/j.tet.2008.11.078},

number = {5},

pages = {1033--1039},

doi = {10.1016/j.tet.2008.11.078}

}

MLA

Cite this

MLA Copy

Du, Lin, et al. “New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp..” Tetrahedron, vol. 65, no. 5, Jan. 2009, pp. 1033-1039. https://doi.org/10.1016/j.tet.2008.11.078.

Publisher

Elsevier

Journal

Tetrahedron

scimago Q3

wos Q2

SJR

0.426

CiteScore

4.1

Impact factor

2.2

ISSN

00404020 (Print)

14645416 (Electronic)