Journal of Chromatography A, volume 239, pages 301-322

Compilation of gas chromatographic retention indices of 163 metabolically important organic acids, and their use in detection of patients with organic acidurias

Publication typeJournal Article
Publication date1982-04-01
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.1
ISSN00219673, 18733778
Organic Chemistry
Biochemistry
General Medicine
Analytical Chemistry
Abstract
Gas chromatographic retention indices have been compiled for 163 metabolically important compounds (mostly organic acids) in the form of methylene units, as trimethylsilyl derivatives, on 10% OV-1 and 10% OV-17 columns. Comprehensive references on metabolic diseases that can be diagnosed by detection of these metabolites are cross-indexed to facilitate the use of the methylene-unit list. The gas chromatographic method, which utilizes extraction of urine with ethyl acetate and trimethylsilylations, is described. Modified methods, one for neutral compounds and one for highly polar organic acids, both of which utilize appropriate ion exchange and lyophilization, are also described. Practical applications of these methods and the use of the methylene-unit in the diagnosis of eleven patients with various metabolic disorders are also shown.

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GOST Copy
Tanaka K., Hine D. G. Compilation of gas chromatographic retention indices of 163 metabolically important organic acids, and their use in detection of patients with organic acidurias // Journal of Chromatography A. 1982. Vol. 239. pp. 301-322.
GOST all authors (up to 50) Copy
Tanaka K., Hine D. G. Compilation of gas chromatographic retention indices of 163 metabolically important organic acids, and their use in detection of patients with organic acidurias // Journal of Chromatography A. 1982. Vol. 239. pp. 301-322.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/s0021-9673(00)81990-1
UR - https://doi.org/10.1016/s0021-9673(00)81990-1
TI - Compilation of gas chromatographic retention indices of 163 metabolically important organic acids, and their use in detection of patients with organic acidurias
T2 - Journal of Chromatography A
AU - Tanaka, Kay
AU - Hine, David G
PY - 1982
DA - 1982/04/01 01:00:00
PB - Elsevier
SP - 301-322
VL - 239
SN - 0021-9673
SN - 1873-3778
ER -
BibTex
Cite this
BibTex Copy
@article{1982_Tanaka,
author = {Kay Tanaka and David G Hine},
title = {Compilation of gas chromatographic retention indices of 163 metabolically important organic acids, and their use in detection of patients with organic acidurias},
journal = {Journal of Chromatography A},
year = {1982},
volume = {239},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/s0021-9673(00)81990-1},
pages = {301--322},
doi = {10.1016/s0021-9673(00)81990-1}
}
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