том 258 издание 2 страницы 343-345

The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles

Тип публикацииJournal Article
Дата публикации1989-12-04
SCImago Q1
Tоп 10% SCImago
WOS Q2
БС1
SJR1.181
CiteScore6.1
Impact factor3
ISSN00145793, 18733468
Biochemistry
Molecular Biology
Cell Biology
Genetics
Structural Biology
Biophysics
Краткое описание

It has been suggested to use surfactant micelles as microcontainers for increasing the efficiency of neuroleptic targeting from blood flow into the brain. The neuroleptic action of haloperidol, intraperitoneally injected into mice in micellar solution of non‐ionic block copolymer surfactant (pluronic P‐85) in water, increased several‐fold if compared with that observed for haloperidol aqueous solution. Incorporation of brain‐specific antibodies into haloperidol‐containing micelles resulted in additional drastic increase (more than by 2 orders of magnitude) in the drug effect.

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ГОСТ |
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KABANOV A. et al. The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles // FEBS Letters. 1989. Vol. 258. No. 2. pp. 343-345.
ГОСТ со всеми авторами (до 50) Скопировать
KABANOV A., Chekhonin V. P., Alakhov V. Yu., Batrakova E. V., Lebedev A. S., Melik-Nubarov N., Arzhakov S. A., Levashov A. V., Morozov G. V., Severin E. S., Kabanov V. The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles // FEBS Letters. 1989. Vol. 258. No. 2. pp. 343-345.
RIS |
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TY - JOUR
DO - 10.1016/0014-5793(89)81689-8
UR - https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793(89)81689-8
TI - The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles
T2 - FEBS Letters
AU - KABANOV, A.V.
AU - Chekhonin, V. P.
AU - Alakhov, V Yu
AU - Batrakova, E V
AU - Lebedev, A. S.
AU - Melik-Nubarov, N.S.
AU - Arzhakov, S A
AU - Levashov, A V
AU - Morozov, G V
AU - Severin, E S.
AU - Kabanov, V.A.
PY - 1989
DA - 1989/12/04
PB - Wiley
SP - 343-345
IS - 2
VL - 258
PMID - 2599097
SN - 0014-5793
SN - 1873-3468
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{1989_KABANOV,
author = {A.V. KABANOV and V. P. Chekhonin and V Yu Alakhov and E V Batrakova and A. S. Lebedev and N.S. Melik-Nubarov and S A Arzhakov and A V Levashov and G V Morozov and E S. Severin and V.A. Kabanov},
title = {The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles},
journal = {FEBS Letters},
year = {1989},
volume = {258},
publisher = {Wiley},
month = {dec},
url = {https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793(89)81689-8},
number = {2},
pages = {343--345},
doi = {10.1016/0014-5793(89)81689-8}
}
MLA
Цитировать
KABANOV, A.V., et al. “The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles.” FEBS Letters, vol. 258, no. 2, Dec. 1989, pp. 343-345. https://febs.onlinelibrary.wiley.com/doi/10.1016/0014-5793(89)81689-8.
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