Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane
Publication type: Journal Article
Publication date: 2023-03-01
scimago Q3
wos Q3
SJR: 0.305
CiteScore: 3.0
Impact factor: 1.7
ISSN: 09599436, 1364551X
General Chemistry
Abstract
New nanocomposites based on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane (APS), including those using N-(phosphonomethyl)iminodiacetic acid (PMIDA), were obtained, and the immobilization of the antitumor agent doxorubicin (Dox) on nanocomposites was examined. It has been shown that the binding of Dox to the negatively charged surface of SiO2 particles occurs more efficiently than that to the APS-modified surface with positively charged amino groups; the presence of PMIDA molecules on the surface significantly increased the loading content. Based on DFT calculations, a mechanism for Dox binding to the surface of the synthesized nanocomposites was proposed.
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Demin A. V. et al. Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 160-163.
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Demin A. V., Vakhrushev A., Valova M. S., Korolyova M. A., Uimin M. A., Minin A. S., Chistyakov K. A., Krasnov V. P., Charushin V. N. Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 160-163.
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RIS
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TY - JOUR
DO - 10.1016/j.mencom.2023.02.004
UR - https://doi.org/10.1016/j.mencom.2023.02.004
TI - Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane
T2 - Mendeleev Communications
AU - Demin, Alexander V.
AU - Vakhrushev, Alexander
AU - Valova, Marina S
AU - Korolyova, Marina A.
AU - Uimin, Mikhail A
AU - Minin, Artem S
AU - Chistyakov, Konstantin A
AU - Krasnov, Victor P.
AU - Charushin, Valery N.
PY - 2023
DA - 2023/03/01
PB - OOO Zhurnal "Mendeleevskie Soobshcheniya"
SP - 160-163
IS - 2
VL - 33
SN - 0959-9436
SN - 1364-551X
ER -
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BibTex (up to 50 authors)
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@article{2023_Demin,
author = {Alexander V. Demin and Alexander Vakhrushev and Marina S Valova and Marina A. Korolyova and Mikhail A Uimin and Artem S Minin and Konstantin A Chistyakov and Victor P. Krasnov and Valery N. Charushin},
title = {Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {OOO Zhurnal "Mendeleevskie Soobshcheniya"},
month = {mar},
url = {https://doi.org/10.1016/j.mencom.2023.02.004},
number = {2},
pages = {160--163},
doi = {10.1016/j.mencom.2023.02.004}
}
Cite this
MLA
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Demin, Alexander V., et al. “Features of doxorubicin adsorption on Fe3O4 magnetic nanoparticles coated with SiO2 or SiO2/aminopropylsilane.” Mendeleev Communications, vol. 33, no. 2, Mar. 2023, pp. 160-163. https://doi.org/10.1016/j.mencom.2023.02.004.