Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum
Publication type: Journal Article
Publication date: 2008-12-01
scimago Q1
wos Q1
SJR: 0.726
CiteScore: 6.9
Impact factor: 3.4
ISSN: 00319422, 18733700
PubMed ID:
19007951
Biochemistry
Molecular Biology
General Medicine
Plant Science
Horticulture
Abstract
Leaves and flowers of Artemisia gorgonum (Asteraceae) collected in Fogo, Cape Verde islands, were phytochemically investigated and resulted in isolation and characterization of three guaianolides 1, 2, 5, and a secoguainolide 4, in addition to eight known guaianolides 6-11 and two known germacranolides 12, 13. Structures were elucidated by 1D and 2D NMR experiments. Careful examination of the (13)C NMR spectrum led to revision of the structure of a previously described guaianolide from 2 to 3. Most compounds exhibited mild antiplasmodial activities, ridentin (13) being the most interesting with an IC(50) of 3.8+/-0.7microgml(-1) against Plasmodium falciparum FcB1 and weak cytotoxicity in a vero cell line (IC(50) 71.0+/-3.9microgml(-1)).
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Total citations:
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GOST
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Ortet R. et al. Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum // Phytochemistry. 2008. Vol. 69. No. 17. pp. 2961-2965.
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Ortet R., Prado S., Mouray E., Thomas O. Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum // Phytochemistry. 2008. Vol. 69. No. 17. pp. 2961-2965.
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TY - JOUR
DO - 10.1016/j.phytochem.2008.09.022
UR - https://doi.org/10.1016/j.phytochem.2008.09.022
TI - Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum
T2 - Phytochemistry
AU - Ortet, Risoleta
AU - Prado, Soizic
AU - Mouray, E.
AU - Thomas, Olivier
PY - 2008
DA - 2008/12/01
PB - Elsevier
SP - 2961-2965
IS - 17
VL - 69
PMID - 19007951
SN - 0031-9422
SN - 1873-3700
ER -
Cite this
BibTex (up to 50 authors)
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@article{2008_Ortet,
author = {Risoleta Ortet and Soizic Prado and E. Mouray and Olivier Thomas},
title = {Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum},
journal = {Phytochemistry},
year = {2008},
volume = {69},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.phytochem.2008.09.022},
number = {17},
pages = {2961--2965},
doi = {10.1016/j.phytochem.2008.09.022}
}
Cite this
MLA
Copy
Ortet, Risoleta, et al. “Sesquiterpene lactones from the endemic Cape Verdean Artemisia gorgonum.” Phytochemistry, vol. 69, no. 17, Dec. 2008, pp. 2961-2965. https://doi.org/10.1016/j.phytochem.2008.09.022.