Lactones: Classification, synthesis, biological activities, and industrial applications
Publication type: Journal Article
Publication date: 2021-03-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
This review summarizes the current knowledge on lactones, a class of biologically active natural products isolated from a wide range of living organisms. Butenolide, 5,6-dihydropyran-2-one, and sesquiterpene lactones display an impressive variety of bioactivities and are the most abundant in nature. This paper provides a compilation of ring construction strategies for the synthesis of small, medium, and macrolactones and discusses their biological activities and industrial, pharmaceutical, and agrochemical applications. • This review summarizes the current knowledge on lactones. • Lactones display an impressive variety of bioactivities. • Simple, medium lactonic rings to macrolactones were stereoselectively synthesized. • Lactone family have received considerable attention from the scientific community.
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131
Total citations:
131
Citations from 2025:
41
(32.03%)
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GOST
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Sartori S. K., Diaz M. A. N., Diaz G. Lactones: Classification, synthesis, biological activities, and industrial applications // Tetrahedron. 2021. Vol. 84. p. 132001.
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Sartori S. K., Diaz M. A. N., Diaz G. Lactones: Classification, synthesis, biological activities, and industrial applications // Tetrahedron. 2021. Vol. 84. p. 132001.
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RIS
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TY - JOUR
DO - 10.1016/j.tet.2021.132001
UR - https://doi.org/10.1016/j.tet.2021.132001
TI - Lactones: Classification, synthesis, biological activities, and industrial applications
T2 - Tetrahedron
AU - Sartori, Suélen Karine
AU - Diaz, Marisa Alves Nogueira
AU - Diaz, Gaspar
PY - 2021
DA - 2021/03/01
PB - Elsevier
SP - 132001
VL - 84
SN - 0040-4020
SN - 1464-5416
ER -
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@article{2021_Sartori,
author = {Suélen Karine Sartori and Marisa Alves Nogueira Diaz and Gaspar Diaz},
title = {Lactones: Classification, synthesis, biological activities, and industrial applications},
journal = {Tetrahedron},
year = {2021},
volume = {84},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.tet.2021.132001},
pages = {132001},
doi = {10.1016/j.tet.2021.132001}
}