volume 17 issue 14 pages 3398-3401

Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.

Publication typeJournal Article
Publication date2015-06-30
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A general strategy for the synthesis of polycyclic polyprenylated acylphloroglucinols is described in which a scalable, Lewis acid catalyzed epoxide-opening cascade cyclization is used to furnish common intermediate 4. The utility of this approach is exemplified by the total syntheses of both ent-nemorosone and (+)-secohyperforin, which were each accomplished in four steps from this intermediate.
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GOST |
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GOST Copy
Sparling B. A. et al. Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin. // Organic Letters. 2015. Vol. 17. No. 14. pp. 3398-3401.
GOST all authors (up to 50) Copy
Sparling B. A., Tucker J. K., Moebius D. C., Shair M. D. Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin. // Organic Letters. 2015. Vol. 17. No. 14. pp. 3398-3401.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.5b01121
UR - https://doi.org/10.1021/acs.orglett.5b01121
TI - Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.
T2 - Organic Letters
AU - Sparling, Brian A.
AU - Tucker, James K
AU - Moebius, David C
AU - Shair, Matthew D
PY - 2015
DA - 2015/06/30
PB - American Chemical Society (ACS)
SP - 3398-3401
IS - 14
VL - 17
PMID - 26125288
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Sparling,
author = {Brian A. Sparling and James K Tucker and David C Moebius and Matthew D Shair},
title = {Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/acs.orglett.5b01121},
number = {14},
pages = {3398--3401},
doi = {10.1021/acs.orglett.5b01121}
}
MLA
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MLA Copy
Sparling, Brian A., et al. “Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin..” Organic Letters, vol. 17, no. 14, Jun. 2015, pp. 3398-3401. https://doi.org/10.1021/acs.orglett.5b01121.