Organic Letters, volume 17, issue 2, pages 173-175

Ruthenium-catalyzed reductive amination without an external hydrogen source.

Publication typeJournal Article
Publication date2014-12-31
Journal: Organic Letters
scimago Q1
SJR1.245
CiteScore9.3
Impact factor4.9
ISSN15237060, 15237052
PubMed ID:  25549756
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A ruthenium-catalyzed reductive amination without an external hydrogen source has been developed using carbon monoxide as the reductant and ruthenium(III) chloride (0.008-2 mol %) as the catalyst. The method was applied to the synthesis of antianxiety agent ladasten.

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