Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin.
Тип публикации: Journal Article
Дата публикации: 2015-10-02
scimago Q1
wos Q1
БС1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
26430796
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
New, highly stable tricyclic antitubercular ozonides 9 and 10 derived from artemisinin are reported in 39 and 9% yields, respectively. The ozonide groups of 9 and 10 were found to be stable under strong basic and acidic conditions. The absolute configuration of ozonides 9 was confirmed by X-ray crystallography. Ozonide 10 shows promising antitubercular activity against M. tuberculosis H37Ra and M. tuberculosis H37Rv with MIC values of 0.39 and 3.12 μg/mL, respectively.
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Chaudhary S. et al. Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin. // Organic Letters. 2015. Vol. 17. No. 20. pp. 4948-4951.
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Chaudhary S., Sharma V., Jaiswal P. K. Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin. // Organic Letters. 2015. Vol. 17. No. 20. pp. 4948-4951.
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TY - JOUR
DO - 10.1021/acs.orglett.5b02296
UR - https://doi.org/10.1021/acs.orglett.5b02296
TI - Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin.
T2 - Organic Letters
AU - Chaudhary, Sandeep
AU - Sharma, Vashundhra
AU - Jaiswal, Pradeep K
PY - 2015
DA - 2015/10/02
PB - American Chemical Society (ACS)
SP - 4948-4951
IS - 20
VL - 17
PMID - 26430796
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (до 50 авторов)
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@article{2015_Chaudhary,
author = {Sandeep Chaudhary and Vashundhra Sharma and Pradeep K Jaiswal},
title = {Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin.},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/acs.orglett.5b02296},
number = {20},
pages = {4948--4951},
doi = {10.1021/acs.orglett.5b02296}
}
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MLA
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Chaudhary, Sandeep, et al. “Stable Tricyclic Antitubercular Ozonides Derived from Artemisinin..” Organic Letters, vol. 17, no. 20, Oct. 2015, pp. 4948-4951. https://doi.org/10.1021/acs.orglett.5b02296.