Journal of the American Chemical Society, volume 141, issue 4, pages 1494-1497
11-Step Total Synthesis of Teleocidins B-1–B-4
Publication type: Journal Article
Publication date: 2019-01-13
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 15
ISSN: 00027863, 15205126
PubMed ID:
30636411
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Abstract
A unified and modular approach to the teleocidin B family of natural products is presented that proceeds in 11 steps and features an array of interesting strategies and methods. Indolactam V, the known biosynthetic precursor to this family, was accessed through electrochemical amination, Cu-mediated aziridine opening, and a remarkable base-induced macrolactamization. Guided by a desire to minimize concession steps, the tactical combination of C-H borylation and a Sigman-Heck transform enabled the convergent, stereocontrolled synthesis of the teleocidins.
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Citations by publishers
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5
10
15
20
25
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Wiley
24 publications, 38.1%
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American Chemical Society (ACS)
18 publications, 28.57%
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Royal Society of Chemistry (RSC)
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Elsevier
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Springer Nature
2 publications, 3.17%
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Thieme
2 publications, 3.17%
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Pharmaceutical Society of Japan
1 publication, 1.59%
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Society of Synthetic Organic Chemistry
1 publication, 1.59%
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American Association for the Advancement of Science (AAAS)
1 publication, 1.59%
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5
10
15
20
25
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Nakamura H. et al. 11-Step Total Synthesis of Teleocidins B-1–B-4 // Journal of the American Chemical Society. 2019. Vol. 141. No. 4. pp. 1494-1497.
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Nakamura H., Yasui K., Kanda Y., Baran P. S. 11-Step Total Synthesis of Teleocidins B-1–B-4 // Journal of the American Chemical Society. 2019. Vol. 141. No. 4. pp. 1494-1497.
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TY - JOUR
DO - 10.1021/jacs.8b13697
UR - https://doi.org/10.1021/jacs.8b13697
TI - 11-Step Total Synthesis of Teleocidins B-1–B-4
T2 - Journal of the American Chemical Society
AU - Baran, Phil S
AU - Nakamura, Hugh
AU - Yasui, Kosuke
AU - Kanda, Yuzuru
PY - 2019
DA - 2019/01/13 00:00:00
PB - American Chemical Society (ACS)
SP - 1494-1497
IS - 4
VL - 141
PMID - 30636411
SN - 0002-7863
SN - 1520-5126
ER -
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@article{2019_Nakamura,
author = {Phil S Baran and Hugh Nakamura and Kosuke Yasui and Yuzuru Kanda},
title = {11-Step Total Synthesis of Teleocidins B-1–B-4},
journal = {Journal of the American Chemical Society},
year = {2019},
volume = {141},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/jacs.8b13697},
number = {4},
pages = {1494--1497},
doi = {10.1021/jacs.8b13697}
}
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MLA
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Nakamura, Hugh, et al. “11-Step Total Synthesis of Teleocidins B-1–B-4.” Journal of the American Chemical Society, vol. 141, no. 4, Jan. 2019, pp. 1494-1497. https://doi.org/10.1021/jacs.8b13697.
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