Nature Materials, volume 4, issue 6, pages 435-446
Quantum dot bioconjugates for imaging, labelling and sensing
1
Center for Bio/Molecular Science and Engineering, Code 6900, US Naval Research Laboratory, Washington, USA
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2
Division of Optical Sciences, Code 5611, US Naval Research Laboratory, Washington, USA
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Publication type: Journal Article
Publication date: 2005-06-01
Journal:
Nature Materials
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 41.2
ISSN: 14761122, 14764660
DOI:
10.1038/nmat1390
General Chemistry
Condensed Matter Physics
General Materials Science
Mechanical Engineering
Mechanics of Materials
Abstract
One of the fastest moving and most exciting interfaces of nanotechnology is the use of quantum dots (QDs) in biology. The unique optical properties of QDs make them appealing as in vivo and in vitro fluorophores in a variety of biological investigations, in which traditional fluorescent labels based on organic molecules fall short of providing long-term stability and simultaneous detection of multiple signals. The ability to make QDs water soluble and target them to specific biomolecules has led to promising applications in cellular labelling, deep-tissue imaging, assay labelling and as efficient fluorescence resonance energy transfer donors. Despite recent progress, much work still needs to be done to achieve reproducible and robust surface functionalization and develop flexible bioconjugation techniques. In this review, we look at current methods for preparing QD bioconjugates as well as presenting an overview of applications. The potential of QDs in biology has just begun to be realized and new avenues will arise as our ability to manipulate these materials improves.
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Citations by publishers
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Medintz I. L. et al. Quantum dot bioconjugates for imaging, labelling and sensing // Nature Materials. 2005. Vol. 4. No. 6. pp. 435-446.
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Medintz I. L., Uyeda H. T., Goldman E. R., Mattoussi H. Quantum dot bioconjugates for imaging, labelling and sensing // Nature Materials. 2005. Vol. 4. No. 6. pp. 435-446.
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TY - JOUR
DO - 10.1038/nmat1390
UR - https://doi.org/10.1038/nmat1390
TI - Quantum dot bioconjugates for imaging, labelling and sensing
T2 - Nature Materials
AU - Medintz, Igor L
AU - Uyeda, H. Tetsuo
AU - Goldman, Ellen R.
AU - Mattoussi, Hedi
PY - 2005
DA - 2005/06/01 00:00:00
PB - Springer Nature
SP - 435-446
IS - 6
VL - 4
SN - 1476-1122
SN - 1476-4660
ER -
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@article{2005_Medintz,
author = {Igor L Medintz and H. Tetsuo Uyeda and Ellen R. Goldman and Hedi Mattoussi},
title = {Quantum dot bioconjugates for imaging, labelling and sensing},
journal = {Nature Materials},
year = {2005},
volume = {4},
publisher = {Springer Nature},
month = {jun},
url = {https://doi.org/10.1038/nmat1390},
number = {6},
pages = {435--446},
doi = {10.1038/nmat1390}
}
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MLA
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Medintz, Igor L., et al. “Quantum dot bioconjugates for imaging, labelling and sensing.” Nature Materials, vol. 4, no. 6, Jun. 2005, pp. 435-446. https://doi.org/10.1038/nmat1390.