Милан Эйнджел Эсколано

Angel Millan was graduated in chemistry in the University of Zaragoza in 1982. He got the PhD in chemistry in the University of Balearic Islands in 1990. The subject of his doctoral thesis was the formation of calcium oxalate renal calculi and the main results were the development of a photometric method for the analysis of citrate in urine, a HPLC chromatographic method for the analysis of oxalate in urine, the inhibition of oxalate crystal growth by polycarboxylic acids, and the finding of an outstanding inhibitor that was patented, commercialized and used in therapy. He studied the kinetics of growth of calcium oxalate during a 4-month postdoc stay in the Institute of Inorganic Chemistry of Czechoslovakia, and the morphology of calcium oxalate monohydrate during 2 years stay in the University of Nijmegen. Then he was contracted for two years by the University of Nijmegen to carry out a project for the firm Agfa-Gevaert on the mechanisms of formation of tabular silver halide crystals that derived in two international patents for the production of tabular photographic emulsions. He stayed, within the human capital and mobility program of the EC, in the IMPCNRS of Perpignan working on the development of refrigerators based on ammoniac, and in the Odeillo solar furnace in the simulation of chemical vapor deposition multicrystalline coatings. In 1996 he moved to the Institute of Materials Science of Aragón and stayed there until nowadays. He was working on the synthesis of semimagnetic-semiconductors, and molecular magnetic materials. Then he developed synthesis methods for the production of iron oxide nanoparticles in polymer matrixes, and strategies for the coating, liquid dispersion and multifunctionalization of magnetic nanoparticles. He became a permanent member of CSIC in 2007. Recently, he developed in cooperation with the University of Aveiro an intracellular nanothemometer and measure the temperature distribution in a live cell. Later he contributed to the fabrication of a nanoprobe that it is at the same time a nanothermometer and a nanoheater. This tool was used to revealed the local temperature of a magnetic nanoheater inside a cell under magnetic hyperthermia. Actually, his main area of interest is intracellular nanothermometry and local magnetic hyperthermia for cancer therapy.