Nature

, volume 607 , issue 7918 , pages 313-320

Grey wolf genomic history reveals a dual ancestry of dogs

Anders Bergström ¹

David W. G. Stanton ^{2, 3, 4}

Ulrike H Taron ⁵

Laurent A. F. Frantz ^{4, 6}

Mikkel-Holger S. Sinding ^{7, 8, 9, 10}

Erik Ersmark ^{2, 3}

Saskia Pfrengle ^{11, 12}

Molly Cassatt Johnstone ¹³

Ophélie Lebrasseur ¹⁴

Linus Girdland Flink ^{15, 16}

Joana M Fernandes ^{17, 18}

Morgane Ollivier ¹⁹

Leo Speidel ^{1, 20}

Shyam Gopalakrishnan ⁷

M. V. Westbury ^{5, 7}

Ramos-Madrigal J ⁷

Tatiana R Feuerborn ^{7, 9, 11}

Ella Reiter ¹¹

Joscha Gretzinger ^{11, 21}

Susanne C Münzel ¹¹

Pooja Swali ¹

Nicholas J. Conard ^{22, 23}

Christian Carøe ⁷

J. M. Haile ¹⁴

Anna Linderholm ^{3, 14, 24, 25}

Semyon Androsov ²⁶

Ian Barnes ²⁷

Chris Baumann ^{23, 28}

Norbert Benecke ²⁹

Hervé Bocherens ^{23, 30}

S Brace ²⁷

Ruth F Carden ³¹

Dorothée G. Drucker ²³

Sergey Fedorov ³²

Mihály Gasparik ³³

Mietje Germonpré ³⁴

Semyon Grigoriev ³²

Pam Groves ³⁵

Stefan T. Hertwig ^{36, 37}

Varvara V Ivanova ³⁸

Luc Janssens ³⁹

RICHARD T. JENNINGS ¹⁶

Aleksei K Kasparov ⁴⁰

Irina V Kirillova ⁴¹

Islam Kurmaniyazov ⁴²

Yaroslav V Kuzmin ⁴³

Pavel A Kosintsev ⁴⁴

Martina Lázničková Galetová ⁴⁵

Charlotte Leduc ⁴⁶

Pavel Nikolskiy ⁴⁷

Marc Nussbaumer ³⁶

Cóilín Odrisceoil ⁴⁸

Ludovic Orlando ⁴⁹

Alan K. Outram ⁵⁰

Elena Y Pavlova ⁵¹

Angela M. Perri ^{52, 53}

Małgorzata Pilot ⁵⁴

Vladimir V Pitulko ⁴⁰

Valerii V Plotnikov ⁵⁵

Albert V Protopopov ⁵⁵

André Rehazek ³⁶

Mikhail V. Sablin ⁵⁶

Andaine Seguin-Orlando ⁴⁹

Jan Storå ⁵⁷

Christian Verjux ⁵⁸

Victor F Zaibert ⁵⁹

Grant Zazula ^{60, 61}

Philippe Crombé ⁶²

Anders K. Hansen ⁷

Eske Willerslev ^{7, 63}

Jennifer Leonard ⁶⁴

Anders Götherström ^{3, 57}

Ron Pinhasi ^{17, 65}

Verena J. Schuenemann ^{11, 12, 17}

Michael Hofreiter ⁵

M. Thomas. P. Gilbert ^{7, 66}

Beth Shapiro ^{13, 67}

Greger Larson ¹⁴

Johannes Krause ⁶⁸

Love Dalén ^{2, 3}

Pontus Skoglund ¹

Hide authors affiliations Show authors affiliations: 68 affiliations

Ancient Genomics Laboratory, The Francis Crick Institute, London, UK |

Department of Bioinformatics and Genetics, Swedish Museum of Natural History, Stockholm, Sweden |

Centre for Palaeogenetics, Stockholm, Sweden |

⁴

School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK |

⁵

Evolutionary Adaptive Genomics, Institute of Biochemistry and Biology, University of Potsdam, Potsdam, Germany |

⁶

Palaeogenomics Group, Department of Veterinary Sciences, Ludwig Maximilian University, Munich, Germany |

⁷

The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark |

⁸

Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland |

⁹

The Qimmeq Project, University of Greenland, Nuuk, Greenland |

¹⁰

Greenland Institute of Natural Resources, Nuuk, Greenland |

¹¹

Institute for Archaeological Sciences, University of Tübingen, Tübingen, Germany |

¹²

Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland |

¹³

Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, Santa Cruz, USA |

¹⁴

The Palaeogenomics & Bio-Archaeology Research Network, Research Laboratory for Archaeology and History of Art, University of Oxford, Oxford, UK |

¹⁵

Department of Archaeology, School of Geosciences, University of Aberdeen, Aberdeen, UK |

¹⁶

School of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK |

¹⁷

Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria |

¹⁸

CIAS, Department of Life Sciences, University of Coimbra, Coimbra, Portugal |

¹⁹

University of Rennes, CNRS, ECOBIO (Ecosystèmes, biodiversité, évolution)–UMR 6553, Rennes, France |

²⁰

Genetics Institute, University College London, London, UK |

²¹

Max Planck Institute for the Science of Human History, Jena, Germany |

²²

Department of Early Prehistory and Quaternary Ecology, University of Tübingen, Tübingen, Germany |

²³

Senckenberg Centre for Human Evolution and Palaeoenvironment, University of Tübingen, Tübingen, Germany |

²⁴

Texas A&M University, College station, USA |

²⁵

Department of Geological Sciences, Stockholm University, Stockholm, Sweden |

²⁶

Museum ‘Severnyi Mir’, Yakutsk, Russian Federation |

²⁷

Department of Earth Sciences, Natural History Museum, London, UK |

²⁸

Department of Geosciences and Geography, Faculty of Science, University of Helsinki, Helsinki, Finland |

²⁹

German Archaeological Institute, Berlin, Germany |

³⁰

Biogeology, Department of Geosciences, University of Tübingen, Tübingen, Germany |

³¹

School of Archaeology, University College Dublin, Dublin, Ireland |

³²

North-Eastern Federal University, Yakutsk, Russian Federation |

³³

Hungarian Natural History Museum, Budapest, Hungary |

³⁴

Royal Belgian Institute of Natural Sciences, Brussels, Belgium |

³⁵

University of Alaska, Fairbanks, USA |

³⁶

Naturhistorisches Museum Bern, Bern, Switzerland |

³⁷

Institute of Ecology and Evolution, University of Bern, Bern, Switzerland |

³⁸

VNIIOkeangeologiya, St Petersburg, Russian Federation |

³⁹

University of Leiden, Leiden, the Netherlands |

⁴⁰

Institute for the History of Material Culture, Russian Academy of Sciences, St Petersburg, Russian Federation |

⁴¹

Ice Age Museum, Shidlovskiy National Alliance ‘Ice Age’, Moscow, Russian Federation |

⁴²

Department of Archaeology, Ethnology and Museology, Al-Farabi Kazakh State University, Almaty, Kazakhstan |

⁴³

Sobolev Institute of Geology and Mineralogy, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation |

⁴⁴

Ural Federal University, Yekaterinburg, Russian Federation |

⁴⁵

Moravian Museum, Brno, Czech Republic |

⁴⁶

INRAP, Metz, France |

⁴⁷

Geological Institute, Russian Academy of Sciences, Moscow, Russian Federation |

⁴⁸

National Monuments Service, Department of Housing, Local Government and Heritage, Dublin, Ireland |

⁴⁹

Centre d’Anthropobiologie et de Génomique de Toulouse UMR 5288, CNRS, Faculté de Médecine Purpan, Université Paul Sabatier, Toulouse, France |

⁵⁰

Department of Archaeology, University of Exeter, Exeter, UK |

⁵¹

Arctic & Antarctic Research Institute, St Petersburg, Russian Federation |

⁵²

PaleoWest, Henderson, USA |

⁵³

Department of Anthropology, University of Nevada, Las Vegas, Las Vegas, USA |

⁵⁴

Museum & Institute of Zoology, Polish Academy of Sciences, Gdańsk, Poland |

⁵⁵

Academy of Sciences of Sakha Republic, Yakutsk, Russian Federation |

⁵⁶

Zoological Institute of the Russian Academy of Sciences, St. Petersburg, Russian Federation |

⁵⁷

Stockholm University, Stockholm, SWEDEN |

⁵⁸

Service Régional de l’Archéologie, Orléans, France |

⁵⁹

Institute of Archaeology and Steppe Civilizations, Al-Farabi Kazakh National University, Almaty, Kazakhstan |

⁶⁰

Yukon Palaeontology Program, Whitehorse, Canada |

⁶¹

Collections and Research, Canadian Museum of Nature, Ottawa, Canada |

⁶²

Department of Archaeology, Ghent University, Ghent, Belgium |

⁶³

Department of Zoology, University of Cambridge, Cambridge, uk |

⁶⁴

Estación Biológica de Doñana (EBD-CSIC), Sevilla, Spain |

⁶⁵

Human Evolution and Archaeological Sciences, University of Vienna, Vienna, Austria |

⁶⁶

University Museum, NTNU, Trondheim, Norway |

⁶⁷

Howard Hughes Medical Institute, University of California, Santa Cruz, Santa Cruz, USA

University of California, Santa Cruz

Howard Hughes Medical Institute

⁶⁸

Max Planck Institute For Evolutionary Anthropology, Leipzig, Germany |

Publication type: Journal Article

Publication date: 2022-06-29

Springer Nature

Nature

scimago Q1

wos Q1

SJR: 18.288

CiteScore: 78.1

Impact factor: 48.5

ISSN: 00280836, 14764687

DOI: 10.1038/s41586-022-04824-9

Copy DOI

PubMed ID: 35768506

Multidisciplinary

Abstract

The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived^1–8. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000–30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located.

Found

1 citation

Baumann Chris

PhD in Geological and Earth sciences, lecturer, fellow of the Academy of Sciences of Albania

21 publications, 401 citations, 4 reviews

h-index: 9

Hemwati Nandan Bahuguna Garhwal University

Harvard University

Research interests

Paleoecology

1 citation

Zeeb-Lanz Andrea

PhD in Cultural Studies, lecturer

13 publications, 639 citations

Burial customs in prehistory

Celtic Archaeology

Neolithic of Europe

Oppida archaeology

Theory in Archaeology

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Bergström A. et al. Grey wolf genomic history reveals a dual ancestry of dogs // Nature. 2022. Vol. 607. No. 7918. pp. 313-320.

GOST all authors (up to 50) Copy

Bergström A. et al. Grey wolf genomic history reveals a dual ancestry of dogs // Nature. 2022. Vol. 607. No. 7918. pp. 313-320.

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BibTex (up to 50 authors) Copy

@article{2022_Bergström,

author = {Anders Bergström and David W. G. Stanton and Ulrike H Taron and Laurent A. F. Frantz and Mikkel-Holger S. Sinding and Erik Ersmark and Saskia Pfrengle and Molly Cassatt Johnstone and Ophélie Lebrasseur and Linus Girdland Flink and Joana M Fernandes and Morgane Ollivier and Leo Speidel and Shyam Gopalakrishnan and M. V. Westbury and Ramos-Madrigal J and Tatiana R Feuerborn and Ella Reiter and Joscha Gretzinger and Susanne C Münzel and Pooja Swali and Nicholas J. Conard and Christian Carøe and J. M. Haile and Anna Linderholm and Semyon Androsov and Ian Barnes and Chris Baumann and Norbert Benecke and Hervé Bocherens and S Brace and Ruth F Carden and Dorothée G. Drucker and Sergey Fedorov and Mihály Gasparik and Mietje Germonpré and Semyon Grigoriev and Pam Groves and Stefan T. Hertwig and Varvara V Ivanova and Luc Janssens and RICHARD T. JENNINGS and Aleksei K Kasparov and Irina V Kirillova and Islam Kurmaniyazov and Yaroslav V Kuzmin and Pavel A Kosintsev and Martina Lázničková Galetová and Charlotte Leduc and Pavel Nikolskiy and others},

title = {Grey wolf genomic history reveals a dual ancestry of dogs},

journal = {Nature},

year = {2022},

volume = {607},

publisher = {Springer Nature},

month = {jun},

url = {https://doi.org/10.1038/s41586-022-04824-9},

number = {7918},

pages = {313--320},

doi = {10.1038/s41586-022-04824-9}

}

MLA

Cite this

MLA Copy

Bergström, Anders, et al. “Grey wolf genomic history reveals a dual ancestry of dogs.” Nature, vol. 607, no. 7918, Jun. 2022, pp. 313-320. https://doi.org/10.1038/s41586-022-04824-9.

Publisher

Springer Nature

Journal

Nature

scimago Q1

wos Q1

SJR

18.288

CiteScore

78.1

Impact factor

48.5

ISSN

00280836 (Print)

14764687 (Electronic)

Labs

Laboratory of Natural Science Methods in Humanitarian Research

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