Indolocarbazole natural products: occurrence, biosynthesis, and biological activity.
Publication type: Journal Article
Publication date: 2006-11-22
scimago Q1
wos Q1
SJR: 2.463
CiteScore: 22.8
Impact factor: 10.6
ISSN: 02650568, 14604752
DOI:
10.1039/B601930G
PubMed ID:
17119643
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The indolocarbazole family of natural products, including the biosynthetically related bisindolylmaleimides, is reviewed (with 316 references cited). The isolation of indolocarbazoles from natural sources and the biosynthesis of this class of compounds are thoroughly reviewed, including recent developments in molecular genetics, enzymology and metabolic engineering. The biological activities and underlying modes of action displayed by natural and synthetic indolocarbazoles is also presented, with an emphasis on the development of analogs that have entered clinical trials for its future use against cancer or other diseases.
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Metrics
382
Total citations:
382
Citations from 2024:
45
(11.78%)
Cite this
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MLA
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GOST
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Sánchez C., Méndez C., Salas J. L. Indolocarbazole natural products: occurrence, biosynthesis, and biological activity. // Natural Product Reports. 2006. Vol. 23. No. 6. pp. 1007-1045.
GOST all authors (up to 50)
Copy
Sánchez C., Méndez C., Salas J. L. Indolocarbazole natural products: occurrence, biosynthesis, and biological activity. // Natural Product Reports. 2006. Vol. 23. No. 6. pp. 1007-1045.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/B601930G
UR - https://doi.org/10.1039/B601930G
TI - Indolocarbazole natural products: occurrence, biosynthesis, and biological activity.
T2 - Natural Product Reports
AU - Sánchez, César
AU - Méndez, Carmen
AU - Salas, José L.
PY - 2006
DA - 2006/11/22
PB - Royal Society of Chemistry (RSC)
SP - 1007-1045
IS - 6
VL - 23
PMID - 17119643
SN - 0265-0568
SN - 1460-4752
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2006_Sánchez,
author = {César Sánchez and Carmen Méndez and José L. Salas},
title = {Indolocarbazole natural products: occurrence, biosynthesis, and biological activity.},
journal = {Natural Product Reports},
year = {2006},
volume = {23},
publisher = {Royal Society of Chemistry (RSC)},
month = {nov},
url = {https://doi.org/10.1039/B601930G},
number = {6},
pages = {1007--1045},
doi = {10.1039/B601930G}
}
Cite this
MLA
Copy
Sánchez, César, et al. “Indolocarbazole natural products: occurrence, biosynthesis, and biological activity..” Natural Product Reports, vol. 23, no. 6, Nov. 2006, pp. 1007-1045. https://doi.org/10.1039/B601930G.