Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum
Yu-Lin Sun
1
,
Jie Bao
1
,
KAI-SHENG LIU
2
,
Xiao-Yong Zhang
1
,
Fei He
1
,
Yi-Fei Wang
2
,
Xu-Hua Nong
1
,
Shu-Hua Qi
1
Тип публикации: Journal Article
Дата публикации: 2013-09-13
scimago Q2
wos Q2
БС1
SJR: 0.427
CiteScore: 4.5
Impact factor: 2.0
ISSN: 00320943, 14390221
PubMed ID:
24037588
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Краткое описание
Two new dihydrothiophene-condensed chromones and a new natural chromone, namely oxalicumones A-C (1-3), respectively, were isolated from a culture broth of a marine-derived fungus, Penicillium oxalicum. The structures of 1-3 and acetylated derivatives of 1 (4-7) were elucidated on the basis of spectroscopic methods and chemical reactions. The absolute configuration of 1 and 2 were established by using the modified Mosher ester method and circular dichroism data of an in situ formed [Rh2(OCOCF3)4] and [Mo2(OAc)4] complex. (R)-MTPA ester of 1 showed cytotoxicity against A375, SW-620, and HeLa carcinoma cell lines with IC50 values of 8.9, 7.8, and 18.4 µM, respectively. Compound 1 displayed cytotoxicity against A375 and SW-620 cell lines with IC50 values of 11.7 and 22.6 µM, respectively. The structure-biological activity relationship of 1 was discussed.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Топ-30
Журналы
|
1
2
3
4
5
6
7
8
|
|
|
Marine Drugs
8 публикаций, 14.04%
|
|
|
Molecular Medicine Reports
2 публикации, 3.51%
|
|
|
Molecules
2 публикации, 3.51%
|
|
|
European Journal of Organic Chemistry
2 публикации, 3.51%
|
|
|
Chemistry and Biodiversity
2 публикации, 3.51%
|
|
|
Journal of Organic Chemistry
2 публикации, 3.51%
|
|
|
Journal of Natural Products
2 публикации, 3.51%
|
|
|
Natural Product Reports
2 публикации, 3.51%
|
|
|
Journal of Asian Natural Products Research
2 публикации, 3.51%
|
|
|
Natural Product Communications
1 публикация, 1.75%
|
|
|
Journal of Fungi
1 публикация, 1.75%
|
|
|
Frontiers in Microbiology
1 публикация, 1.75%
|
|
|
Marine Life Science & Technology
1 публикация, 1.75%
|
|
|
Archives of Pharmacal Research
1 публикация, 1.75%
|
|
|
Archives of Microbiology
1 публикация, 1.75%
|
|
|
Medicinal Chemistry Research
1 публикация, 1.75%
|
|
|
Phytochemistry Reviews
1 публикация, 1.75%
|
|
|
Mycological Progress
1 публикация, 1.75%
|
|
|
Fitoterapia
1 публикация, 1.75%
|
|
|
European Journal of Pharmacology
1 публикация, 1.75%
|
|
|
Phytochemistry Letters
1 публикация, 1.75%
|
|
|
Bioorganic and Medicinal Chemistry Letters
1 публикация, 1.75%
|
|
|
Journal of Organometallic Chemistry
1 публикация, 1.75%
|
|
|
Chemical Reviews
1 публикация, 1.75%
|
|
|
Journal of the American Chemical Society
1 публикация, 1.75%
|
|
|
Journal of Medicinal Chemistry
1 публикация, 1.75%
|
|
|
Russian Journal of Bioorganic Chemistry
1 публикация, 1.75%
|
|
|
Natural Product Research
1 публикация, 1.75%
|
|
|
Journal of Industrial Microbiology and Biotechnology
1 публикация, 1.75%
|
|
|
1
2
3
4
5
6
7
8
|
Издатели
|
2
4
6
8
10
12
|
|
|
MDPI
11 публикаций, 19.3%
|
|
|
Elsevier
9 публикаций, 15.79%
|
|
|
Springer Nature
7 публикаций, 12.28%
|
|
|
American Chemical Society (ACS)
7 публикаций, 12.28%
|
|
|
Wiley
5 публикаций, 8.77%
|
|
|
Royal Society of Chemistry (RSC)
3 публикации, 5.26%
|
|
|
Taylor & Francis
3 публикации, 5.26%
|
|
|
Spandidos Publications
2 публикации, 3.51%
|
|
|
Frontiers Media S.A.
2 публикации, 3.51%
|
|
|
SAGE
1 публикация, 1.75%
|
|
|
Pharmaceutical Society of Korea
1 публикация, 1.75%
|
|
|
Pleiades Publishing
1 публикация, 1.75%
|
|
|
Westerdijk Fungal Biodiversity Institute
1 публикация, 1.75%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 публикация, 1.75%
|
|
|
2
4
6
8
10
12
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
57
Всего цитирований:
57
Цитирований c 2024:
9
(15.79%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
Sun Y. et al. Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum // Planta Medica. 2013. Vol. 79. No. 15. pp. 1474-1479.
ГОСТ со всеми авторами (до 50)
Скопировать
Sun Y., Bao J., LIU K., Zhang X., He F., Wang Y., Nong X., Qi S. Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum // Planta Medica. 2013. Vol. 79. No. 15. pp. 1474-1479.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1055/s-0033-1350805
UR - https://doi.org/10.1055/s-0033-1350805
TI - Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum
T2 - Planta Medica
AU - Sun, Yu-Lin
AU - Bao, Jie
AU - LIU, KAI-SHENG
AU - Zhang, Xiao-Yong
AU - He, Fei
AU - Wang, Yi-Fei
AU - Nong, Xu-Hua
AU - Qi, Shu-Hua
PY - 2013
DA - 2013/09/13
PB - Georg Thieme Verlag KG
SP - 1474-1479
IS - 15
VL - 79
PMID - 24037588
SN - 0032-0943
SN - 1439-0221
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2013_Sun,
author = {Yu-Lin Sun and Jie Bao and KAI-SHENG LIU and Xiao-Yong Zhang and Fei He and Yi-Fei Wang and Xu-Hua Nong and Shu-Hua Qi},
title = {Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum},
journal = {Planta Medica},
year = {2013},
volume = {79},
publisher = {Georg Thieme Verlag KG},
month = {sep},
url = {https://doi.org/10.1055/s-0033-1350805},
number = {15},
pages = {1474--1479},
doi = {10.1055/s-0033-1350805}
}
Цитировать
MLA
Скопировать
Sun, Yu-Lin, et al. “Cytotoxic Dihydrothiophene-Condensed Chromones from the Marine-Derived Fungus Penicillium oxalicum.” Planta Medica, vol. 79, no. 15, Sep. 2013, pp. 1474-1479. https://doi.org/10.1055/s-0033-1350805.