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Enediyne antibiotics and their models: new potential of acetylene chemistry

Тип публикацииJournal Article
Дата публикации2006-09-30
scimago Q1
wos Q1
БС1
SJR0.811
CiteScore12.9
Impact factor6
ISSN0036021X, 14684837
General Chemistry
Краткое описание
Structures and chemical properties of enediynes, viz., compounds comprising a system of conjugated double and triple bonds, are surveyed. The presence of this system in the molecules of enediyne antitumour antibiotics ensures their high activity. The mechanism of biological action of enediynes is discussed based on cycloaromatisation of the enediyne chromophore resulting in highly active benzenoid 1,4-diradicals, which selectively cleave DNA. The key strategies of enediyne synthesis are analysed.
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ГОСТ |
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Maretina I. A., Trofimov B. A. Enediyne antibiotics and their models: new potential of acetylene chemistry // Russian Chemical Reviews. 2006. Vol. 75. No. 9. pp. 825-845.
ГОСТ со всеми авторами (до 50) Скопировать
Maretina I. A., Trofimov B. A. Enediyne antibiotics and their models: new potential of acetylene chemistry // Russian Chemical Reviews. 2006. Vol. 75. No. 9. pp. 825-845.
RIS |
Цитировать
TY - JOUR
DO - 10.1070/RC2006v075n09ABEH002479
UR - https://doi.org/10.1070/RC2006v075n09ABEH002479
TI - Enediyne antibiotics and their models: new potential of acetylene chemistry
T2 - Russian Chemical Reviews
AU - Maretina, Irina A
AU - Trofimov, Boris A.
PY - 2006
DA - 2006/09/30
PB - Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
SP - 825-845
IS - 9
VL - 75
SN - 0036-021X
SN - 1468-4837
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2006_Maretina,
author = {Irina A Maretina and Boris A. Trofimov},
title = {Enediyne antibiotics and their models: new potential of acetylene chemistry},
journal = {Russian Chemical Reviews},
year = {2006},
volume = {75},
publisher = {Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii},
month = {sep},
url = {https://doi.org/10.1070/RC2006v075n09ABEH002479},
number = {9},
pages = {825--845},
doi = {10.1070/RC2006v075n09ABEH002479}
}
MLA
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Maretina, Irina A., and Boris A. Trofimov. “Enediyne antibiotics and their models: new potential of acetylene chemistry.” Russian Chemical Reviews, vol. 75, no. 9, Sep. 2006, pp. 825-845. https://doi.org/10.1070/RC2006v075n09ABEH002479.